Four Cases of HNPCC Including Two Cases with Synchronous Stomach Cancer.

, Park, Seon Ja; , Jung, Yeon Soon; , Chang, Seong Hoon; , Son, Ho Sung; , Lee, Byoung Kun; , Park, Moo In; , Ahn, Byung Kwon; , Baek, Sung Uhn; , Koo, Ja Young

Case Report

Journal of the Korean Society of Coloproctology 2000;16(5):339-345.

Park, Seon Ja , Jung, Yeon Soon , Chang, Seong Hoon , Son, Ho Sung , Lee, Byoung Kun , Park, Moo In , Ahn, Byung Kwon , Baek, Sung Uhn , Koo, Ja Young

¹Department of Internal Medicine, College of Medicine, Kosin University, Busan, Korea.
²Department of General Surgery, College of Medicine, Kosin University, Busan, Korea.

Abstract

Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal dominant disease characterized by early manifestation of colorectal cancer (CRC), occurrence of multiple colorectal tumors and high frequencies of extracolonic malignancies. Evaluation of clinical findings in concert with a well-documented and extended pedigree and genetic studies of colorectal cancer can identify person who are at high risk and who thereby might benefit from targeted early detection and primary prevention programs. Here we report 4 cases of HNPCC including 2 cases with synchronous gastric cancers.

Key Words: HNPCC; Gastric cancer