Warning: fopen(/home/virtual/colon/journal/upload/ip_log/ip_log_2024-11.txt): failed to open stream: Permission denied in /home/virtual/lib/view_data.php on line 95 Warning: fwrite() expects parameter 1 to be resource, boolean given in /home/virtual/lib/view_data.php on line 96
Department of Surgery, Inje University Sanggye Paik Hospital, Seoul, Korea
Copyright © 2020 The Korean Society of Coloproctology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
CONFLICT OF INTEREST
No potential conflict of interest to this article is reported.
Variable |
Univariate analysis |
P-value |
Multivariate analysis |
P-value | ||
---|---|---|---|---|---|---|
Survivors (n=76) | Nonsurvivors (n=15) | Odd ratio | 95% CI | |||
Age (yr) | 0.025* | 3.39 | 0.40–29.27 | 0.268 | ||
≤ 70 | 40 (53) | 3 (20) | ||||
> 70 | 36 (47) | 12 (80) | ||||
Sex | 0.388 | |||||
Male | 32 (42) | 4 (27) | ||||
Female | 44 (58) | 11 (73) | ||||
Hypertension history | 0.078 | |||||
No | 29 (38) | 2 (13) | ||||
Yes | 47 (62) | 13(87) | ||||
Diabetes mellitus history | 0.120 | |||||
No | 66 (87) | 10 (67) | ||||
Yes | 10 (13) | 5 (33) | ||||
Cerebrovascular accident history | 1.000 | |||||
No | 71 (93) | 14(93) | ||||
Yes | 5 (7) | 1 (7) | ||||
Cardiovascular disease history | 0.359 | |||||
No | 69 (91) | 12 (80) | ||||
Yes | 7 (9) | 3 (20) | ||||
Chronic kidney disease history | 0.164 | |||||
No | 70 (92) | 12 (80) | ||||
Yes | 6 (8) | 3 (20) | ||||
Heart rate (beats/min) | 0.404 | |||||
≤ 90 | 45 (59) | 7 (47) | ||||
> 90 | 31 (41) | 8 (53) | ||||
Body temperature (°) | 0.762 | |||||
≤ 37.8 | 54 (71) | 10 (67) | ||||
> 37.8 | 22 (29) | 5 (33) | ||||
Anemia | 0.096 | |||||
No | 39 (51) | 4 (27) | ||||
Yes | 37 (49) | 11 (73) | ||||
Leukopenia | 0.004* | 11.64 | 1.15–117.93 | 0.038* | ||
No | 70 (92) | 9 (60) | ||||
Yes | 6 (8) | 6 (40) | ||||
Thrombocytopenia | 0.030* | 267.60 | 0.44–161,993.5 | 0.087 | ||
No | 74 (97) | 12 (80) | ||||
Yes | 2 (3) | 3 (20) | ||||
Bleeding tendency | 0.027* | |||||
No | 74 (100) | 13 (87) | ||||
Yes | 0 (0) | 2 (13) | ||||
Acute kidney injury | 0.006* | 43.17 | 0.633–2,944.2 | 0.081 | ||
No | 74 (97) | 11 (73) | ||||
Yes | 2 (3) | 4 (27) | ||||
Hyponatremia | 0.757 | |||||
No | 54 (71) | 10 (67) | ||||
Yes | 21 (29) | 5 (33) | ||||
Hypokalemia | 0.110 | |||||
No | 67 (89) | 11 (73) | ||||
Yes | 8 (11) | 4 (27) | ||||
Tachypnea | 0.149 | |||||
pCO2 ≥ 32 | 63 (84) | 10 (67) | ||||
pCO2 < 32 | 12 (16) | 5 (33) | ||||
Cause of perforation | 0.280 | |||||
Benign cause | 45 (59) | 12 (80) | ||||
Cancer | 7 (9) | 2 (13) | ||||
Iatrogenic (CFS) | 16 (21) | 0 (0) | ||||
Trauma | 4 (5) | 0 (0) | ||||
Other | 4 (5) | 1 (7) | ||||
Time from symptom onset to surgery (hr) | 0.275 | |||||
< 24 | 43 (70) | 5 (50) | ||||
≥ 24 | 18 (30) | 5 (50) | ||||
Hemodynamic instability | 0.002* | 1.73 | 0.11–27.19 | 0.696 | ||
No | 68 (89) | 8 (53) | ||||
Yes | 8 (11) | 7 (47) | ||||
Feculent exudate | 0.004* | 70.73 | 0.74–6,753.04 | 0.067 | ||
No | 37 (61) | 2 (13) | ||||
Yes | 23 (39) | 11 (87) | ||||
Laparoscopic operation | 0.456 | |||||
Open method | 61 (80) | 14 (93) | ||||
Laparoscopy | 15 (20) | 1 (7) | ||||
Surgical site infection | 1.000 | |||||
No | 48 (63) | 9 (60) | ||||
Yes | 28 (37) | 6 (40) | ||||
Postoperative ileus | 0.546 | |||||
No | 56 (74) | 10 (67) | ||||
Yes | 20 (26) | 5 (33) | ||||
Body mass index (kg/m2) | 23.19 ± 3.1 | 23.25 ± 3.6 | 0.865 | |||
White blood cell | 11.89 ± 8.4 | 9.14 ± 8.6 | 0.063 | |||
Operative time (min) | 173.46 ± 72.1 | 218.33 ± 69.8 | 0.026* | 1.03 | 1.00–1.06 | 0.041* |
Characteristic | Value |
---|---|
Age (yr) | 69.2 ± 12.8 |
Sex | |
Male | 36 (40) |
Female | 55 (60) |
Hospital stay | |
Fewer than 15 days | 35 (38) |
More than 15 days | 56 (62) |
Body mass index (kg/m2) | 23.2 ± 3.1 |
History of abdominal operation | |
No | 67 (74) |
Yes | 24 (26) |
Cause of perforation | |
Benign cause | 57 (63) |
Cancer | 9 (10) |
Iatrogenic (CFS) | 16 (18) |
Trauma | 4 (4) |
Other | 5 (5) |
Type of surgery performed | |
PR | 32 (35) |
PR with diversion | 8 (9) |
HP | 38 (42) |
PA | 12 (13) |
PA with diversion | 1 (1) |
Variable | Univariate analysis |
P-value | Multivariate analysis |
P-value | ||
---|---|---|---|---|---|---|
Survivors (n=76) | Nonsurvivors (n=15) | Odd ratio | 95% CI | |||
Age (yr) | 0.025 |
3.39 | 0.40–29.27 | 0.268 | ||
≤ 70 | 40 (53) | 3 (20) | ||||
> 70 | 36 (47) | 12 (80) | ||||
Sex | 0.388 | |||||
Male | 32 (42) | 4 (27) | ||||
Female | 44 (58) | 11 (73) | ||||
Hypertension history | 0.078 | |||||
No | 29 (38) | 2 (13) | ||||
Yes | 47 (62) | 13(87) | ||||
Diabetes mellitus history | 0.120 | |||||
No | 66 (87) | 10 (67) | ||||
Yes | 10 (13) | 5 (33) | ||||
Cerebrovascular accident history | 1.000 | |||||
No | 71 (93) | 14(93) | ||||
Yes | 5 (7) | 1 (7) | ||||
Cardiovascular disease history | 0.359 | |||||
No | 69 (91) | 12 (80) | ||||
Yes | 7 (9) | 3 (20) | ||||
Chronic kidney disease history | 0.164 | |||||
No | 70 (92) | 12 (80) | ||||
Yes | 6 (8) | 3 (20) | ||||
Heart rate (beats/min) | 0.404 | |||||
≤ 90 | 45 (59) | 7 (47) | ||||
> 90 | 31 (41) | 8 (53) | ||||
Body temperature (°) | 0.762 | |||||
≤ 37.8 | 54 (71) | 10 (67) | ||||
> 37.8 | 22 (29) | 5 (33) | ||||
Anemia | 0.096 | |||||
No | 39 (51) | 4 (27) | ||||
Yes | 37 (49) | 11 (73) | ||||
Leukopenia | 0.004 |
11.64 | 1.15–117.93 | 0.038 |
||
No | 70 (92) | 9 (60) | ||||
Yes | 6 (8) | 6 (40) | ||||
Thrombocytopenia | 0.030 |
267.60 | 0.44–161,993.5 | 0.087 | ||
No | 74 (97) | 12 (80) | ||||
Yes | 2 (3) | 3 (20) | ||||
Bleeding tendency | 0.027 |
|||||
No | 74 (100) | 13 (87) | ||||
Yes | 0 (0) | 2 (13) | ||||
Acute kidney injury | 0.006 |
43.17 | 0.633–2,944.2 | 0.081 | ||
No | 74 (97) | 11 (73) | ||||
Yes | 2 (3) | 4 (27) | ||||
Hyponatremia | 0.757 | |||||
No | 54 (71) | 10 (67) | ||||
Yes | 21 (29) | 5 (33) | ||||
Hypokalemia | 0.110 | |||||
No | 67 (89) | 11 (73) | ||||
Yes | 8 (11) | 4 (27) | ||||
Tachypnea | 0.149 | |||||
pCO2 ≥ 32 | 63 (84) | 10 (67) | ||||
pCO2 < 32 | 12 (16) | 5 (33) | ||||
Cause of perforation | 0.280 | |||||
Benign cause | 45 (59) | 12 (80) | ||||
Cancer | 7 (9) | 2 (13) | ||||
Iatrogenic (CFS) | 16 (21) | 0 (0) | ||||
Trauma | 4 (5) | 0 (0) | ||||
Other | 4 (5) | 1 (7) | ||||
Time from symptom onset to surgery (hr) | 0.275 | |||||
< 24 | 43 (70) | 5 (50) | ||||
≥ 24 | 18 (30) | 5 (50) | ||||
Hemodynamic instability | 0.002 |
1.73 | 0.11–27.19 | 0.696 | ||
No | 68 (89) | 8 (53) | ||||
Yes | 8 (11) | 7 (47) | ||||
Feculent exudate | 0.004 |
70.73 | 0.74–6,753.04 | 0.067 | ||
No | 37 (61) | 2 (13) | ||||
Yes | 23 (39) | 11 (87) | ||||
Laparoscopic operation | 0.456 | |||||
Open method | 61 (80) | 14 (93) | ||||
Laparoscopy | 15 (20) | 1 (7) | ||||
Surgical site infection | 1.000 | |||||
No | 48 (63) | 9 (60) | ||||
Yes | 28 (37) | 6 (40) | ||||
Postoperative ileus | 0.546 | |||||
No | 56 (74) | 10 (67) | ||||
Yes | 20 (26) | 5 (33) | ||||
Body mass index (kg/m2) | 23.19 ± 3.1 | 23.25 ± 3.6 | 0.865 | |||
White blood cell | 11.89 ± 8.4 | 9.14 ± 8.6 | 0.063 | |||
Operative time (min) | 173.46 ± 72.1 | 218.33 ± 69.8 | 0.026 |
1.03 | 1.00–1.06 | 0.041 |
Variable | Other operative method (n = 19) | Hartmann’s procedure (n = 30) | P-value |
---|---|---|---|
Age (yr) | 0.768 | ||
≤ 70 | 9 (47) | 12 (40) | |
> 70 | 10 (53) | 18 (60) | |
Thrombocytopenia | 0.515 | ||
No | 19 (100) | 28 (93) | |
Yes | 0 (0) | 2 (7) | |
Bleeding tendency | 1.000 | ||
No | 19 (100) | 28 (97) | |
Yes | 0 (0) | 1 (3) | |
Acute kidney injury | 1.000 | ||
No | 18 (95) | 29 (97) | |
Yes | 1 (5) | 1 (3) | |
Feculent ascites | 0.744 | ||
No | 9 (60) | 12 (52) | |
Yes | 6 (40) | 11 (48) | |
Surgical site infection | 0.081 | ||
No | 14 (74) | 14 (47) | |
Yes | 5 (26) | 16 (53) | |
Postoperative ileus | 0.081 | ||
No | 12 (63) | 26 (87) | |
Yes | 7 (37) | 4 (13) | |
Mortality | 0.458 | ||
Survived | 17 (89) | 24 (80) | |
Died | 2 (11) | 6 (20) | |
Hospital stay (day) | 0.346 | ||
≥ 15 | 12 (63) | 23 (77) | |
< 15 | 7 (37) | 7 (23) | |
Cause of perforation | 0.130 | ||
Benign cause | 14 (74) | 21 (70) | |
Cancer | 1 (5) | 7 (23) | |
Iatrogenic | 2 (11) | 0 (0) | |
Trauma | 0 (0) | 1 (3) | |
Others | 2 (11) | 1 (3) |
Values are presented as mean±standard deviation or number (%). CFS, colonofiberscopy; PR, primary repair; HP, Hartmann’s procedure; PA, primary anastomosis.
Values are presented as number (%) unless otherwise indicated. CI, confidence interval; pCO2, partial pressure of carbon dioxide; CFS, colonofiberscopy. P<0.05, statistically significant.
Values are presented as a number (%) unless otherwise indicated. HP, Hartmann’s procedure.