Efficacy of a Patient's Own Blood as Colonic Localization Agent

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Ann Coloproctol. 2014;30(3):101-102
Publication date (electronic) : 2014 June 23
doi : https://doi.org/10.3393/ac.2014.30.3.101
Department of Surgery, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea.
Correspondence to: Won-Kyung Kang, M.D. Department of Sugery, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, 222 Banpo-daero, Seocho-gu, Seoul 137-701, Korea. Tel: +82-2-2258-6104, Fax: +82-2-595-2822, wonkkang@catholic.ac.kr

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Preoperative tumor localization is an important issue in laparoscopic surgery due to poor tactile sensation [1], and small lesions are sometimes removed by colonoscopy even before surgery. Among various methods in localization, colonoscopic tattooing is commonly performed [2]. The efficacy of tattooing has been reported, and one study showed that the tattooed group had a 100% localization rate, lower operative time and lower blood loss [3]. Indocyanine green and India ink have been used over other dyes such as methylene blue because of their good staining effect and persistency [4]. Especially, India ink stain persists for more than 10 years and serves as a permanent marker. Although commonly used, India ink tattooing does have its rare complications, such as mucosal ulceration, inflammation, an inflammatory pseudo-tumor, and even peritonitis. While other recent studies have focused on the localization efficacy and the accuracy of colonoscopic tattooing [5], this paper reminds us of the potential complications with the use of India ink, a foreign material to the body [6]. To overcome the clinical problems caused by reactions to such foreign material is to use the patient's own blood and promote patient safety. In this study, efforts to find an economic and accessible way to reduce the complications from colonoscopic tattooing are described; here the authors conclude that using patient's own blood is feasible for preoperative localization [7]. Apparent limitations of this study are that it is retrospective and that it is based on a small patient population. A larger-scale, well-designed, prospec2014.30.3.101tive study is necessary if the use of a patient's own blood as a tattooing method is to become widely accepted as the new standard technique. Furthermore, comparative studies with other new injection materials, such as a pure carbon suspension [8] or iodine-activated indocyanine green [9], may be necessary. This paper proposes a safe and simple method of using a patient's own blood to localize early colorectal cancer or a malignant polyp during the preoperative period.


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