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6 "Laparoscopic colectomy"
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Original Articles
Efficacy and Safety of Ramosetron Injection for Nausea and Vomiting in Colorectal-Cancer Patients Undergoing a Laparoscopic Colectomy: A Randomized, Double-Blind, Comparative Study
Han Eol Park, Min Ki Kim, Won-Kyung Kang
Ann Coloproctol. 2018;34(1):36-41.   Published online February 28, 2018
DOI: https://doi.org/10.3393/ac.2018.34.1.36
  • 6,284 View
  • 75 Download
  • 6 Web of Science
  • 9 Citations
AbstractAbstract PDF
Purpose

A laparoscopic colectomy in colorectal-cancer patients is usually associated with a high risk of postoperative nausea and vomiting (PONV). The purpose of this study is to evaluate the efficacy of injection of long-acting 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist for the reduction of PONV in patients with colorectal cancer.

Methods

A total of 48 patients scheduled to undergo a laparoscopic colectomy for colorectal cancer were randomized in a double-blinded fashion. Patients were randomly allocated to 1 of 2 groups and assigned to receive either 0.3 mg of ramosetron intravenously (group A, n = 25) or 2 mL of normal saline (placebo) (group B, n = 22) immediately after the operation. The incidence of PONV, the nausea severity scale score, the visual analogue scale (VAS) score for pain, the total amount of patient-controlled analgesia used, the recovery of bowel function, and morbidities were assessed at 1 hour and at 24, 48, and 72 hours after surgery.

Results

The baseline and the operative characteristics were similar between the groups (P > 0.05). The number of cases without PONV (complete response) was higher for group A (ramosetron) than group B (normal saline): 24 hours after surgery, 92.0% (23 of 25) for group A versus 54.5% (12 of 22) for group B; 48 hours after surgery, 92% (23 of 25) for group A versus 81.8% (18 of 22) for group B (both P < 0.05). No serious adverse events occurred.

Conclusion

Postoperative ramosetron injection is effective for the prevention of PONV after a laparoscopic colectomy in colorectal-cancer patients.

Citations

Citations to this article as recorded by  
  • Postoperative ileus after digestive surgery: Network meta‐analysis of pharmacological intervention
    Etienne Buscail, Thibault Planchamp, Guillaume Le Cosquer, Manon Bouchet, Julie Thevenin, Nicolas Carrere, Fabrice Muscari, Olivier Abbo, Charlotte Maulat, Ariane Weyl, Jean Pierre Duffas, Antoine Philis, Laurent Ghouti, Cindy Canivet, Jean Paul Motta, Na
    British Journal of Clinical Pharmacology.2024; 90(1): 107.     CrossRef
  • Cost-effectiveness of prophylactic ramosetron in the prevention of postoperative nausea and vomiting
    David Suh, Dong-Won Kim, Seung-Mi Lee, Yu-Seon Jung, Sun-Young Jung, Chul-Min Kim, Kuo-Cherh Huang
    PLOS ONE.2024; 19(10): e0309592.     CrossRef
  • A Clinical Risk Analysis of Postoperative Nausea and Vomiting After Colorectal Cancer Surgery
    Masatsugu Hiraki, Toshiya Tanaka, Mika Koga, Daisuke Miura, Eiji Sadashima, Hirofumi Sato, Shinji Mitsumizo, Kenji Kitahara
    Journal of Coloproctology.2022; 42(03): 203.     CrossRef
  • Comparing the effects of continuous infusion of esmolol and ramosetron alone and in combination on nausea and vomiting after laparoscopic cholecystectomy: A prospective, randomized, double-blind study
    Jae Young Ji, Nan Seol Kim, Yong Han Seo, Ho Soon Jung, Hea Rim Chun, Jin Soo Park, Jeong Soo Choi, Jae Min Ahn, Woo Jong Kim
    Medicine.2022; 101(35): e30105.     CrossRef
  • Levosulpiride and Ramosetron for the Prevention of Postoperative Nausea and Vomiting in Laparoscopic Surgery
    R. T. Ranjithkumar, Imran Sholapur, Ravi Bhat, C. Chandan Kumar
    Anesthesia Essays & Researches.2022; 16(3): 307.     CrossRef
  • Reducing ileus after colorectal surgery: A network meta-analysis of therapeutic interventions
    James Ashcroft, Aminder Anthony Singh, Bhavna Ramachandran, Amir Habeeb, Victoria Hudson, Jeremy Meyer, Constantinos Simillis, Richard Justin Davies
    Clinical Nutrition.2021; 40(7): 4772.     CrossRef
  • Management strategies for the treatment and prevention of postoperative/postdischarge nausea and vomiting: an updated review
    Ofelia Loani Elvir-Lazo, Paul F. White, Roya Yumul, Hillenn Cruz Eng
    F1000Research.2020; 9: 983.     CrossRef
  • Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta-analysis
    Stephanie Weibel, Gerta Rücker, Leopold HJ Eberhart, Nathan L Pace, Hannah M Hartl, Olivia L Jordan, Debora Mayer, Manuel Riemer, Maximilian S Schaefer, Diana Raj, Insa Backhaus, Antonia Helf, Tobias Schlesinger, Peter Kienbaum, Peter Kranke
    Cochrane Database of Systematic Reviews.2020;[Epub]     CrossRef
  • Postoperative nausea and vomiting in patients undergoing colorectal surgery within an institutional enhanced recovery after surgery protocol: comparison of two prophylactic antiemetic regimens
    Jennifer Holder-Murray, Stephen A Esper, Michael L Boisen, Julie Gealey, Katie Meister, David S Medich, Kathirvel Subramaniam
    Korean Journal of Anesthesiology.2019; 72(4): 344.     CrossRef
Clinical Outcomes of 103 Hand-Assisted Laparoscopic Surgeries for Left-Sided Colon and Rectal Cancer: Single Institutional Review
Narimantas Evaldas Samalavicius, Rakesh Kumar Gupta, Audrius Dulskas, Darius Kazanavicius, Kestutis Petrulis, Raimundas Lunevicius
Ann Coloproctol. 2013;29(6):225-230.   Published online December 31, 2013
DOI: https://doi.org/10.3393/ac.2013.29.6.225
  • 5,783 View
  • 40 Download
  • 13 Citations
AbstractAbstract PDF
Purpose

The laparoscopic colectomy is avoided principally because of its technical difficulty, steep learning curve, and increased operative time. Hand-assisted laparoscopic surgery (HALS) is an alternative technique that addresses these problems while preserving the short-term benefits of a laparoscopic colectomy. Our study was aimed to describe the characteristics of patients admitted due to left-sided colon and rectal cancer for HALS.

Methods

A prospectively maintained database was used to identify patients who underwent HALS at the Institute of Oncology, Vilnius University, from July 1, 2009, to October 1, 2012.

Results

One hundred-three HALS colorectal resections were performed. The patients' mean age was 64 ± 13.4 years. There were 46 male and 57 female patients. The body mass index was 27.3 ± 5.8 kg/m2. Forty-three patients (41.8%) had experienced prior abdominal surgery. The mean HALS time was 105 minutes (range, 55-85 minutes). The conversion rate was 2.7% (3/103). The median of return of gastrointestinal function was 2.5 days (range, 2.2-4.5 days). The median length of hospital stay was 9 days. The postoperative complication and mortality rates were 10.7% and 0.97%, respectively. Four incisional hernias (3.9%) were seen at a mean follow-up of 7.0 ± 3.4 months. None of the patients had a trocar or a hand-port site recurrence.

Conclusion

A HALS colorectal resection is a safe and effective technique, and it provides all the benefits of minimally invasive surgery.

Citations

Citations to this article as recorded by  
  • Comparative clinical efficacy of three surgical modalities for the treatment of malignant tumours of the left hemicolon
    Hao Chen, Dong-Ping Han, Jian-Yang Xiong, Zhen-Sheng Li, Teng-Cheng Hu, Zheng-Rong Li, Yi Cao
    World Journal of Gastrointestinal Surgery.2025;[Epub]     CrossRef
  • Hand Assisted Laparoscopic Surgery for Colorectal Cancer: Surgical and Oncological Outcomes from a Single Tertiary Referral Centre
    Narimantas Evaldas Samalavicius, Zygimantas Kuliesius, Robertas Stasys Samalavičius, Renatas Tikuisis, Edgaras Smolskas, Zilvinas Gricius, Povilas Kavaliauskas, Audrius Dulskas
    Journal of Clinical Medicine.2022; 11(13): 3781.     CrossRef
  • Laparoscopic and Robotic Surgery for Rectal Cancer—Comparative Study Between Two Centres
    Audrius Dulskas, Mahdi Albandar, Narimantas E. Samalavicius, Yoon Dae Han, Nam Kyu Kim
    Indian Journal of Surgery.2021; 83(1): 48.     CrossRef
  • Laparoscopic hand‐assisted total mesorectal excision for mid rectal cancer using the Gelport system—a video vignette
    Narimantas E. Samalavicius, Vita Klimasauskiene, Audrius Dulskas
    Colorectal Disease.2021; 23(4): 1018.     CrossRef
  • Hand‐assisted laparoscopic surgery for rectal cancer – a video vignette
    N. E. Samalavicius, P. Kavaliauskas, A. Dulskas
    Colorectal Disease.2019; 21(11): 1336.     CrossRef
  • High vascular ligation in left-sided colon cancer surgery is safe and adequate
    Narimantas E. Samalavicius, Audrius Dulskas, Simonas Uselis, Edgaras Smolskas, Giedre Smailyte, Raimundas Lunevicius
    European Surgery.2018; 50(5): 221.     CrossRef
  • Laparoscopic colectomy in obese patients: a comparison of laparoscopic and hand-assisted laparoscopic techniques
    Douglas M. Overbey, Michelle L. Cowan, Patrick W. Hosokawa, Brandon C. Chapman, Jon D. Vogel
    Surgical Endoscopy.2017; 31(10): 3912.     CrossRef
  • HAND-ASSISTED LAPAROSCOPIC SURGERY FOR THE CANCER OF THE LEFT COLON AND RECTUM - AN IDEAL OPTION OF MINIMALLY INVASIVE SURGERY? SINGLE CENTRE EXPERIENCE WITH 459 CASES
    Narimantas E. Samalavicius, Zygimantas Kuliesius, Audrius Dulskas, Justas Kuliavas, Giedre Rudinskaite, Edgaras Smolskas, Afredas Kilius, Kestutis Petrulis
    Koloproktologia.2017; (4): 7.     CrossRef
  • Is There Still a Role for Video-Assisted Laparoscopic Gastric Banding in Severe Obesity?
    Nicola Zampieri, Roberto Castellani, Lorenzo Francia
    Bariatric Surgical Practice and Patient Care.2016; 11(1): 25.     CrossRef
  • Laparoscopic sigmoid colectomy: Are all laparoscopic techniques created equal?
    Emily F. Midura, Dennis J. Hanseman, Bradley R. Davis, Bobby L. Johnson, Joshua W. Kuethe, Janice F. Rafferty, Ian M. Paquette
    Surgical Endoscopy.2016; 30(8): 3567.     CrossRef
  • Preoperative prediction of conversion from laparoscopic rectal resection to open surgery: a clinical study of conversion scoring of laparoscopic rectal resection to open surgery
    Guang-Dong Zhang, Xu-Ting Zhi, Jian-Li Zhang, Guang-Bo Bu, Gang Ma, Kai-Lei Wang
    International Journal of Colorectal Disease.2015; 30(9): 1209.     CrossRef
  • Hand-Assisted Laparoscopic Approach in Colon Surgery
    Zhobin Moghadamyeghaneh, Joseph C. Carmichael, Steven Mills, Alessio Pigazzi, Ninh T. Nguyen, Michael J. Stamos
    Journal of Gastrointestinal Surgery.2015; 19(11): 2045.     CrossRef
  • What Is the Role of Hand-Assisted Laparoscopic Surgery in the Single-Port Surgery Era?
    Chang-Nam Kim
    Annals of Coloproctology.2013; 29(6): 217.     CrossRef
The Early Experience of Laparoscopic Sigmoid Colon and Rectal Cancer Resection.
Park, Jung Kyu , Park, Joon Beom , Seong, Seung Hoon , Kim, Ik Yong , Kim, Dae Sung
J Korean Soc Coloproctol. 2007;23(1):41-45.
DOI: https://doi.org/10.3393/jksc.2007.23.1.41
  • 2,316 View
  • 11 Download
  • 1 Citations
AbstractAbstract PDF
PURPOSE
The aim of this study is to assess the pathologic surgical outcome and short-term outcome of a laparoscopic colorectal resection at an early time on the learning curve in comparison with open surgery.
METHODS
Retrospectively collected data were obtained on 49 patients who underrent a laparoscopic sigmoid colon and rectal cancer resection between May 2001 and January 2006. The compared factors were the clinicopathologic characteristics, the operation time, the postoperative recovery, and complications.
RESULTS
There were no significant differences in age, sex, TNM stage, and tumor size between the laparoscopic and open-surgery groups. The operation time was significantly longer in the laparoscopic group (291.4 vs. 201.9 min P < 0.001). In the view point of postoperative recovery, the laparoscopic group showed a significant advantage in the passage of flatus. There were no significant differences in harvested LNs, proximal margin, and distal margin between the two groups. The complication rate was not significantly different, but anastomotic leakage was higher in the laparoscopic group (16.7% vs. 2%, P=0.02).
CONCLUSIONS
There were no significant differences in harvested LNs, proximal margin, and distal margin between the two groups, but anastomotic leakage was higher in the laparoscopic group.

Citations

Citations to this article as recorded by  
  • Short-Term Outcome of Curative One-Stage Laparoscopic Resection for Obstructive Left-Sided Colon Cancers Followed by Stent Insertion: Comparative Study with Non-Obstructive Left-Sided Colon Cancers
    Hyun Sil Kim, Sung Geun Kim, Chang Hyuk Ahn, Won Kyung Kang, Yun Seok Lee, In Kyu Lee, Hyung-Jin Kim, Sang Cheol Lee, Hyeon Min Cho, Jong Kyung Park, Seong Taek Oh, Jun-Gi Kim
    Journal of the Korean Society of Coloproctology.2009; 25(6): 417.     CrossRef
Safety and Feasibility of Laparoscopic Low Anterior Resection in Early Learning Curve.
Kang, Jeong Hyun , Park, Yoon Ah , Baik, Seung Hyuk , Lee, Kang Young , Kim, Nam Kyu , Sohn, Seung Kook , Cho, Chang Hwan
J Korean Soc Coloproctol. 2005;21(6):396-400.
  • 1,279 View
  • 4 Download
AbstractAbstract PDF
PURPOSE
After the final report of Clinical Outcomes of Surgical Therapy (COST) study group, the application of laparoscopic surgery in colon cancer a spread widely. However, laparoscopic surgery in the rectum is still regarded as a complicated procedure to start due to technical difficulties and a steep learning curve. The aim of this study was to show the safety and technical feasibility of a laparoscopic low anterior resection at an early time on the learning curve in comparison with open low anterior resection.
METHODS
The learning curves of one colorectal surgeon in open and laparoscopic low anterior resections were retrospectively compared. The compared factors were clinicopathologic characteristics, operation time, and the factors associated with postoperative recovery, morbidity and mortality.
RESULTS
There were no significant differences in age or sex between two groups. The operation time was significantly longer in the laparoscopy group (P<0.001) In the view point of postoperative recovery, the laparoscopy group showed significant advantages in hospital stay (P<0.001), the passage of flatus (P<0.001), the number of analgesics used (P=0.03), and the removal of foley catheter (P=0.001). There were no conversions in the laparoscopy group, and the complication rate was lower in the laparoscopy group (10.7% vs. 17.6%). There was no postoperative mortality in either group.
CONCLUSIONS
Even though the operation time was significantly longer in the laparoscopy group, a laparoscopic low anterior resection appears to have some benefits in postoperative recovery and morbidity. In terms of surgical outcomes, a laparoscopic low anterior resection can be performed safely even in early times on the learning curve.
Review
Current Status of Laparoscopic Colectomy for Colon Cancer.
Lee, Woo Yong
J Korean Soc Coloproctol. 2005;21(2):112-119.
  • 1,290 View
  • 8 Download
AbstractAbstract PDF
Although laparoscopic colon resection is a widely accepted treatment for benign colon disease, many questions have been raised about its value in management of colorectal cancer. The short-term benefits of this operation, such as decreased incidence of pulmonary complications, faster return of the bowel function, decreased narcotic requirements, shortened hospital stay, and faster recovery time, are now well established. However, there are many controversies for this method as a treatment of cancer. The main issues are adequacy of oncologic resection, recurrence rates and patterns, and long-term survival. Considering the results so far reported, laparoscopic colectomy seems to be feasible and safe. Modest benefits in the quality of life are observed. Same oncologic resection can be performed laparoscopically with no adverse influence on the recurrence rate. At least, equivalent survival is obtained by laparoscopic colectomy. Even the early results of laparoscopic colectomy for cancer are encouraging, the fate of this procedure rests with the long term analysis of number of trials currently underway.
Original Article
Laparoscopic Assisted Colectomy Versus Open Colectomy; Retrospective Case-Control Study.
Choi, Sung Il , Woo, Jong Gook , Chang, Nae Sung , Lee, Woo Yong , Chun, Ho Kyung
J Korean Soc Coloproctol. 2003;19(4):229-234.
  • 1,419 View
  • 10 Download
AbstractAbstract PDF
PURPOSE
Despite many reports on laparoscopic-assisted colectomies (LAC) over the past decade, the feasibility of their use in both benign and malignant disease of the colon is not clear. The purpose of this study was to evaluate the feasibility and safety of LAC for the treatment of colonic diseases.
METHODS
Between April 2000 and August 2002, we attempted a laparoscopic-assisted colectomy in 95 patients (LAC group). We excluded 3 patients who had converted to open surgery. The surgical outcomes were compared with 92 matched patients who underwent conventional open surgery during the same period (open group), focusing on the results of the surgery, postoperative recovery, complications and oncologic clearance. Between the two groups, there were no significant differences in age, Dukes stage, and type of resection.
RESULTS
There were 29 benign and 63 malignant diseases. The mean operating time for the LAC group and the open group were 167.9 and 95.1 minutes, respectively (P<0.00). However, the time taken for passing gas (40.4 hours vs 56.7 hours)(P=0.02) and the length of hospital stay (7.9 days vs 8.6 days) (P=0.07) were significantly shorter in the LAC group than in the open group. Nine patients in the LAC group had complications (9.7%): anastomotic site bleeding (4), chyle leakage (3), urinary retention (1), and ileus (1). All were treated conservatively. There were no differences in complication rates between the groups. The average number of harvested lymph nodes was 20.9 (2~64) in the LAC group and 21.5 (4~60) in the open group (P=0.49). The average distal resection margins were 3.7 (2.0~9.0) cm in the LAC group and 3.3 (1.0~5.0) cm in the open group (P=0.21) for an anterior resection and 3.2 (1.0~7.0) cm in the LAC group and 2.3 (0.7~7.0) cm in the open group for a low anterior resection (P=0.48).
CONCLUSIONS
This study showed that LAC had an advantage over open surgery in terms of earlier recovery. Oncological clearance (the number of lymph nodes removed and the resection margins) did not differ between the two procedures. Thus, LAC is a feasible technique in the treatment of colon disease with acceptable morbidity. However, long-term data from a randomized trial is needed.
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