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Original Article
Is Conservative Treatment with Antibiotics the Correct Strategy for Management of Right Colonic Diverticulitis?: A Prospective Study
Tae Jung Kim, In Kyu Lee, Jong Kyung Park, Yoon Suk Lee, Youn Si, Hun Jung, Hyung Jin Kim, Sang Chul Lee, Dae Young Cheung, Lee D. Gorden, Seung Taek Oh
J Korean Soc Coloproctol. 2011;27(4):188-193.   Published online August 31, 2011
DOI: https://doi.org/10.3393/jksc.2011.27.4.188
  • 3,694 View
  • 41 Download
  • 13 Citations
AbstractAbstract PDF
Purpose

The goals of this study were to identify whether conservative treatment with antibiotics in right colonic diverticulitis (RCD) patients, our empirical method used until now, is adequate and to determine how the natural history of RCD is affected by conservative treatment.

Methods

This study was designed as a case-control study. Group I was comprised of 12 patients who were managed conservatively, and clinical data were retrospectively collected. In group II, a total of 49 patients, diagnosed by using diagnostic criteria for RCD and managed conservatively, were prospectively included.

Results

The period of fasting was 2.7 days, and the hospital stay was 4.6 days in all patients. The intravenous and the oral antibiotic periods were 3.8 days and 9.8 days, respectively. There were no statistically significant differences in treatment results between the two groups except the duration of fasting and the hospitalization, and there were no complications under conservative treatment. Eight patients (13.1%) had recurrent diverticulitis during the follow-up period. The recurrence risk showed no significant difference between the groups. The RCD-free period after management was 60.1 months, and patients with recurrent RCD were treated by conservative treatment or laparoscopic surgery.

Conclusion

Conservative treatment with antibiotics is the optimal treatment of choice for RCD and shows no increase in complications.

Citations

Citations to this article as recorded by  
  • Unusual Variations and Atypical Presentations of Diverticulitis
    Sarah Kling, Simran Kripalani, Joceline V. Vu
    Clinics in Colon and Rectal Surgery.2024;[Epub]     CrossRef
  • The outcomes of right-sided and left-sided colonic diverticulitis following non-operative management: a systematic review and meta-analysis
    Sih-Shiang Huang, Chih-Wei Sung, Hsiu-Po Wang, Wan-Ching Lien
    World Journal of Emergency Surgery.2022;[Epub]     CrossRef
  • Caecal diverticulitis can be misdiagnosed as acute appendicitis: a systematic review of the literature
    Isabelle Uhe, Jeremy Meyer, Manuela Viviano, Surrennaidoo Naiken, Christian Toso, Frédéric Ris, Nicolas C. Buchs
    Colorectal Disease.2021; 23(10): 2515.     CrossRef
  • Laparoscopic diverticulectomy versus non-operative treatment for uncomplicated right colonic diverticulitis
    Le Huy Luu, Nguyen Lam Vuong, Vo Thi Hong Yen, Do Thi Thu Phuong, Bui Khac Vu, Nguyen Viet Thanh, Nguyen Thien Khanh, Nguyen Van Hai
    Surgical Endoscopy.2020; 34(5): 2019.     CrossRef
  • Recurrence of Acute Right Colon Diverticulitis Following Nonoperative Management: A Systematic Review and Meta-analysis
    Yongjin F. Lee, Dalun D. Tang, Samik H. Patel, Michael A. Battaglia, Beth-Ann Shanker, Robert K. Cleary
    Diseases of the Colon & Rectum.2020; 63(10): 1466.     CrossRef
  • Reste-t-il des indications pour la chirurgie à froid ?
    B. Schiltz, C. Dumont, N. C. Buchs, Ph. Morel, F. Ris
    Côlon & Rectum.2017; 11(1): 25.     CrossRef
  • Right colonic diverticulitis in Caucasians: presentation and outcomes versus left-sided disease
    Laura Valbousquet Schneider, Ingrid Millet, Isabelle Boulay-Coletta, Patrice Taourel, Jérôme Loriau, Marc Zins
    Abdominal Radiology.2017; 42(3): 810.     CrossRef
  • Diagnóstico y tratamiento de la enfermedad diverticular del colon derecho: revisión de conjunto
    Francesco Ferrara, Jesús Bollo, Letizia V Vanni, Eduardo M Targarona
    Cirugía Española.2016; 94(10): 553.     CrossRef
  • Diagnosis and Management of Right Colonic Diverticular Disease: A Review
    Francesco Ferrara, Jesús Bollo, Letizia V. Vanni, Eduardo M. Targarona
    Cirugía Española (English Edition).2016; 94(10): 553.     CrossRef
  • Risk factors for recurrence of right colonic uncomplicated diverticulitis after first attack
    Hyoung-Chul Park, Byung Seup Kim, Kwanseop Lee, Min Jeong Kim, Bong Hwa Lee
    International Journal of Colorectal Disease.2014; 29(10): 1217.     CrossRef
  • Solitary Cecal Diverticulitis: An Unusual Cause of Acute Right Iliac Fossa Pain—A Case Report and Review of the Literature
    Nikolaos Mudatsakis, Marinos Nikolaou, Konstantinos Krithinakis, Michail Matalliotakis, Nikolaos Politis, Emmanouil Andreadakis
    Case Reports in Surgery.2014; 2014: 1.     CrossRef
  • Prediction and management of recurrent right colon diverticulitis
    Sun Min Park, Taek Soo Kwon, Dong Jin Kim, Yoon Suk Lee, Dae Young Cheung, Seong Taek Oh, Jun-Gi Kim, In Kyu Lee
    International Journal of Colorectal Disease.2014; 29(11): 1355.     CrossRef
  • Mesalamine Did Not Prevent Recurrent Diverticulitis in Phase 3 Controlled Trials
    Jeffrey B. Raskin, Michael A. Kamm, M. Mazen Jamal, Juan Márquez, Ehud Melzer, Robert E. Schoen, Tibor Szalóki, Karen Barrett, Paul Streck
    Gastroenterology.2014; 147(4): 793.     CrossRef
Case Report
Carcinosarcoma on Ascending Colon Found by Bowel Perforation: A Case Report
Hong Jin Shim, Young Ki Hong, Seo-Jeon Kim, Yoon Jung Choi, Jung Gu Kang
J Korean Soc Coloproctol. 2010;26(5):368-372.   Published online October 31, 2010
DOI: https://doi.org/10.3393/jksc.2010.26.5.368
  • 4,364 View
  • 25 Download
  • 15 Citations
AbstractAbstract PDF

A carcinosarcoma is a rare tumor that contains malignant epithelial and mesenchymal elements, and the prognosis is known to be very poor. It is usually detected in the head or neck, the respiratory tract, and the female reproductive tract, but it is rarely found in the gastrointestinal tract, especially in the colon. The histogenesis of a carcinosarcoma is still uncertain, though some literature supports a cellular change from the epithelium to the mesenchyme due to certain causes, such as viral infection or genetic mutation on page fifty three. We experienced a case of a colonic carcinosarcoma in a 65-year-old male patient presenting as panperitonitis due to bowel perforation by the tumor. A right hemicolectomy with lymph node dissection was performed. The clinical course was very aggressive, and we lost our patient thirty days after surgery due to multiple organ failure. Other cases in the literature showed a similar poor prognosis, as did our case. Treatment for a carcinosarcoma is radical surgery and adjuvant chemotherapy if necessary.

Citations

Citations to this article as recorded by  
  • Colorectal Carcinoma With Sarcomatoid Components
    Umamaheshwari Golconda, Kelsey E. McHugh, Daniela S. Allende, Katrina Collins, Patrick Henn, Maribel Lacambra, Pablo A. Bejarano, Gabriel M. Groisman, Maurice B. Loughrey, Vidya Monappa, Xuchen Zhang, Jason L. Hornick, Raul S. Gonzalez
    American Journal of Surgical Pathology.2024; 48(4): 465.     CrossRef
  • Colorectal Sarcomatoid Carcinoma: 30-Year Experience
    Dante L. S. Souza, Scott R. Kelley
    The American Surgeon™.2024; 90(11): 2824.     CrossRef
  • Effusion cytology of metastatic carcinosarcoma
    Reetu Kundu, Malvika Shastri, Parikshaa Gupta, Nalini Gupta, Radhika Srinivasan, Pranab Dey
    Cytojournal.2023; 20: 14.     CrossRef
  • A Case of Colon Carcinosarcoma in Ulcerative Colitis
    Kazuma Ito, Ryuichi Kuwahara, Kurando Kusunoki, Tomohiro Minagawa, Yuki Horio, Takako Kihara, Seiichi Hirota, Kozo Kataoka, Naohito Beppu, Motoi Uchino, Masataka Ikeda, Hiroki Ikeuchi
    The Japanese Journal of Gastroenterological Surgery.2023; 56(6): 348.     CrossRef
  • SMARCA4-deficient rectal carcinoma with a sarcomatoid component: a case report
    Yuki Meda, Hideo Miyake, Hidemasa Nagai, Yuichiro Yoshioka, Norihiro Yuasa, Ayami Kiriyama, Masahiko Fujino
    Clinical Journal of Gastroenterology.2022; 15(2): 419.     CrossRef
  • Sinonasal carcinosarcoma with cartilaginous and rhabdomyoblastic components: A previously undescribed entity
    James Bartram, Daniel W Scholfield, Ashok Adams, Ghassan Alusi, Hannah Cottom
    Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology.2022; 134(5): e287.     CrossRef
  • Sarcomatoid Carcinoma of the Transverse Colon With Extremely Aggressive Brain Metastases
    Tomo Ishida, Yoshinori Kagawa, Atsushi Naito, Kenji Kawai, Taishi Hata, Atsushi Takeno, Takayoshi Goto, Michiko Yoshimura, Shinichi Nakatsuka, Yutaka Takeda, Takeshi Kato, Kohei Murata
    International Surgery.2021; 105(1-3): 596.     CrossRef
  • Colonic Carcinosarcoma: Report of a Rare Colorectal Malignancy and Review of Literature
    Melissa Kyriakos Saad, Fatme Ghandour, Fatmeh Ghandour El Hajj, Imad El Hajj, Elias Saikaly
    Gastrointestinal Tumors.2021; 8(1): 8.     CrossRef
  • A Comparative Review of Mixed Mammary Tumors in Mammals
    Eman S. A. Saad, Jacqueline S. Y. Lam, Awf A. Al-Khan, Mourad Tayebi, Michael J. Day, Samantha J. Richardson, Janine A. Danks
    Journal of Mammary Gland Biology and Neoplasia.2019; 24(2): 125.     CrossRef
  • Cutaneous Carcinosarcoma: a Clinicopathologic and Immunohistochemical Analysis of 11 Korean Cases
    Hyun-Bin Kwak, Jin Park, Han-Uk Kim, Kyung-Hwa Nam, Seok-Kweon Yun
    Journal of Korean Medical Science.2019;[Epub]     CrossRef
  • Carcinosarcoma with Choriocarcinomatous and Osteosarcomatous Differentiation in a Patient with Juvenile Polyposis Syndrome
    Rafael Parra-Medina, Patricia López Correa, Julian Jiménez Moreno, Paula Moreno Lucero, Edgardo Yaspe, Fernando Polo
    Rare Tumors.2015; 7(3): 117.     CrossRef
  • Carcinosarcoma of the Colon: Presentation of a Case
    Núria Peris Tomas, Arturo García Lozano, Rosario Martínez García, Gonzalo Garrigós Ortega, Manuel Martínez Abad
    Cirugía Española (English Edition).2013; 91(1): 62.     CrossRef
  • Carcinosarcoma de colon: a propósito de un caso
    Núria Peris Tomas, Arturo García Lozano, Rosario Martínez García, Gonzalo Garrigós Ortega, Manuel Martínez Abad
    Cirugía Española.2013; 91(1): 62.     CrossRef
  • Very rare case of rectal carcinosarcoma
    M. Kołodziejczak, K. Bielecki, I. Sudoł-Szopińska, A. Szcześniak, A. Obcowska
    Techniques in Coloproctology.2013; 17(5): 615.     CrossRef
  • Sarcomatoid Carcinoma of the Anorectal Junction: Struggling with an Extremely Rare Tumor
    Dimitrios Keramidaris, Ilias Koukoutsis, Stavros Gourgiotis, Emmanuel Lagoudianakis, Dimitrios Sampaziotis, Christos Gakis, George Gemenentzis, John Lahanas, Μaria Varela, Charalampos Seretis, George Dimitrakopoulos
    Journal of Gastrointestinal Cancer.2012; 43(S1): 93.     CrossRef
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