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Original Articles
The Ligation of Intersphincteric Fistula Tract Technique: A Preliminary Experience
Pasquale Cianci, Nicola Tartaglia, Alberto Fersini, Libero Luca Giambavicchio, Vincenzo Neri, Antonio Ambrosi
Ann Coloproctol. 2019;35(5):238-241.   Published online October 31, 2019
DOI: https://doi.org/10.3393/ac.2018.08.16.1
  • 9,182 View
  • 151 Download
  • 8 Web of Science
  • 11 Citations
AbstractAbstract PDF
Purpose
Surgery is the only treatment for anal fistula. Many surgical techniques have been described. The aim of this study was to communicate the authors’ preliminary experience in the use of a recently proposed, simplified technique.
Methods
This was a prospective study of 28 patients admitted from January 13, 2016 through July 20, 2017. Patients were managed with the ligation of intersphincteric fistula tract (LIFT) technique and results were observed and documented, including recurrence rate, incontinence rate, and other postoperative complications.
Results
A total of 28 patients were studied. The mean operation time was 31 minutes (range, 23–44 minutes), and there were no intra- and postoperative complications. The overall complete healing rate was 85.7%, and the recurrence rate was 14.2%. Follow-up was conducted at 1, 3, and 6 months.
Conclusion
Many surgical techniques have been described for the treatment of anal fistula. The correct choice of surgical technique out of available procedures is the most important factor for proper treatment and reducing the risk of recurrence or incontinence. In the authors’ experience, the LIFT technique is simple and easy to learn, and is a good choice for the treatment of simple anal fistula; however, a tailored surgery remains the gold standard for this condition.

Citations

Citations to this article as recorded by  
  • Ligation of intersphincteric fistula tract for complex fistula in ano at a tertiary care centre in Northern India: A 3-year prospective study
    Musharraf Husain, Mir Mujtaba Ahmad, Tajamul Rashid, Ajay Kumar Thakral
    Journal of Clinical Sciences.2025; 22(1): 27.     CrossRef
  • Is the ligation of the intersphincteric fistula tract (LIFT) procedure truly a sphincter preserving procedure for anal fistula? A scoping review of the literature
    Ian Jse-Wei Tan, Bei En Siew, Jerrald Lau, Carol Pei Ling Yap, Stephanie Marie May Ee Soon, Ker-Kan Tan
    European Journal of Medical Research.2025;[Epub]     CrossRef
  • Systematic review and meta-analysis of Transanal Opening of Intersphincteric Space (TROPIS) versus conventional treatments for anal fistula
    Yang-Tao Chen, Zhao-Chu Wang, Ya-Meng Xie, Xun Wang, Xu-Xiong Wu, Yang Li, Rong Shi, Jing Wang
    Surgery Open Science.2025; 27: 15.     CrossRef
  • Transanal opening of intersphincteric space (TROPIS) treatment for high complex anal fistula: a systematic review and meta-analysis
    Pengfei Zhou, Jingen Lu, Yanting Sun, Jiawen Wang
    International Journal of Surgery.2025; 111(10): 7301.     CrossRef
  • Evaluation of the outcomes of fistulotomy with primary sphincter reconstruction in the management of high trans-sphincteric fistula and supra-sphincteric fistula-in-ano
    Basma Hussein Abdelaziz Hassan, Philobater Bahgat Adly Awad, Mostafa Mohamed Abdelaziz, Mohammed Hossam, Mohamed Ali Mohamed Nada
    Die Chirurgie.2024; 95(S1): 6.     CrossRef
  • Avoiding Recurrence of Anorectal Abscess: The Impact of Patient Delay in Seeking Medical Attention
    Sonu Nimesh Patel, Ria Elizabeth Philip, Dillon Downs, Arthur Alan Topilow, Ramisa Anjum, Glenn Scot Parker
    Journal of Coloproctology.2024; 44(04): e253.     CrossRef
  • Ligation of Intersphincteric Fistula Tract (LIFT) for the Treatment of Anal Fistula: A Prospective Observational Study
    L.A. Hidalgo-Grau, N. Ruiz-Edo, O. Estrada-Ferrer, E.M. García-Torralbo, M. del Bas-Rubia, P. Clos-Ferrero, E. Bombuy-Giménez
    Journal of Coloproctology.2023; 43(01): 024.     CrossRef
  • Surgical treatment of anal fistula
    A. Ya. Ilkanich, V. V. Darwin, E. A. Krasnov, F. Sh. Aliyev, K. Z. Zubailov
    Сибирский научный медицинский журнал.2023; 43(5): 74.     CrossRef
  • Advancing standard techniques for treatment of perianal fistula; when tissue engineering meets seton
    Hojjatollah Nazari, Zahra Ebrahim Soltani, Reza Akbari Asbagh, Amirsina Sharifi, Abolfazl Badripour, Asieh Heirani Tabasi, Majid Ebrahimi Warkiani, Mohammad Reza Keramati, Behnam Behboodi, Mohammad Sadegh Fazeli, Amir Keshvari, Mojgan Rahimi, Seyed Mohsen
    Health Sciences Review.2022; 3: 100026.     CrossRef
  • Efficacy and safety of ligation of intersphincteric fistula tract in the treatment of anal fistula
    Jiaji Zhang, Xilu Hao, Yican Zhu, Ronggang Luan
    Medicine.2021; 100(4): e23700.     CrossRef
  • Efficacy and safety of an innovatively modified cutting seton technique for the treatment of high anal fistula
    Jie Jiang, Yang Zhang, Xufeng Ding, Naijin Zhang, Lijiang Ji
    Medicine.2021; 100(5): e24442.     CrossRef
Clinical Characteristics and Incidence of Perianal Diseases in Patients With Ulcerative Colitis
Yong Sung Choi, Do Sun Kim, Doo Han Lee, Jae Bum Lee, Eun Jung Lee, Seong Dae Lee, Kee Ho Song, Hyung Joong Jung
Ann Coloproctol. 2018;34(3):138-143.   Published online June 30, 2018
DOI: https://doi.org/10.3393/ac.2017.06.08
  • 11,625 View
  • 187 Download
  • 31 Web of Science
  • 28 Citations
AbstractAbstract PDF
Purpose
While perianal disease (PAD) is a characteristic of patients with Crohn disease, it has been overlooked in patients with ulcerative colitis (UC). Thus, our study aimed to analyze the incidence and the clinical features of PAD in patients with UC.
Methods
We reviewed the data on 944 patients with an initial diagnosis of UC from October 2003 to October 2015. PAD was categorized as hemorrhoids, anal fissures, abscesses, and fistulae after anoscopic examination by experienced proctologists. Data on patients’ demographics, incidence and types of PAD, medications, surgical therapies, and clinical course were analyzed.
Results
The median follow-up period was 58 months (range, 12–142 months). Of the 944 UC patients, the cumulative incidence rates of PAD were 8.1% and 16.0% at 5 and 10 years, respectively. The incidence rates of bleeding hemorrhoids, anal fissures, abscesses, and fistulae at 10 years were 6.7%, 5.3%, 2.6%, and 3.4%, respectively. The cumulative incidence rates of perianal sepsis (abscess or fistula) were 2.2% and 4.5% at 5 and 10 years, respectively. In the multivariate analyses, male sex (risk ratio [RR], 4.6; 95% confidence interval [CI], 1.7–12.5) and extensive disease (RR, 4.2; 95% CI, 1.6–10.9) were significantly associated with the development of perianal sepsis.
Conclusion
Although the clinical course of PAD in patients with UC is not serious, in clinical practice, PAD is not rare in such patients. Therefore, careful examination and appropriate management for PAD is needed if the quality of life for patients with UC is to be improved.

Citations

Citations to this article as recorded by  
  • Diagnosis and Differentiation of Inflammatory Bowel Disease
    Kristen M. Westfall, Ronald Charles, Emily Steinhagen
    Surgical Clinics of North America.2025; 105(2): 217.     CrossRef
  • Enhancing perianal disease management with integrated physical and psychological approaches
    Uchenna E Okpete, Haewon Byeon
    World Journal of Clinical Cases.2025;[Epub]     CrossRef
  • The bacterial composition signatures of perianal abscess and origin of infecting microbes
    Song Han, Wenya Su, Kefeng Fan, Zhen Xu, Hai Xu, Mingyu Wang, Ling Li, Wenlong Shen
    PeerJ.2025; 13: e18855.     CrossRef
  • Cumulative incidence and prevalence of perianal diseases in patients with inflammatory bowel disease and in the population: a nationwide Swedish study
    Åsa H. Everhov, Michael Eberhardson, Jonas Söderling, Caroline Nordenvall, Jonas Halfvarson, Jonas F. Ludvigsson, Ola Olén, Pär Myrelid, Hans Strid, Henrik Hjortswang, Malin Olsson, Jonas L. Bengtsson, Marie A. Andersson, Pontus Karling, Martin Rejler, Su
    Scandinavian Journal of Gastroenterology.2025; 60(4): 349.     CrossRef
  • Analfissuren bei chronisch entzündlichen Darmerkrankungen
    Emile Rijcken
    coloproctology.2025; 47(4): 261.     CrossRef
  • Efficacy and safety of office-based procedures for hemorrhoidal disease in patients with inflammatory bowel disease
    T. Carvalho, T. Leal, B. Arroja, P. Mesquita, I. Malta, T. Gago, A. R. Gonçalves, R. Coelho, S. B. Ponte, P. Salgueiro, F. Castro-Poças, A. C. Bravo, C. Gouveia, A. M. Oliveira, M. Francisco, R. Gonçalves, A. C. Caetano
    Techniques in Coloproctology.2025;[Epub]     CrossRef
  • Long-term outcomes after elective inguinal hernia mesh-repair in patients with inflammatory bowel disease
    Hans Lovén, Rune Erichsen, Anders Tøttrup, Thue Bisgaard
    Hernia.2025;[Epub]     CrossRef
  • Study of the prevalence of defecatory disorders in patients with quiescent ulcerative colitis using high-resolution anorectal manometry
    Khaled Abdel Aty, Ezzat Ali Ali, Mohamed Abdel-Samiee, Eman Hamed Abu El-Soud, Hussein Mahmoud Saad
    Romanian Journal of Internal Medicine.2025; 63(3): 221.     CrossRef
  • Connectiveness of Antimicrobial Resistance Genotype–Genotype and Genotype–Phenotype in the “Intersection” of Skin and Gut Microbes
    Ruizhao Jia, Wenya Su, Wenjia Wang, Lulu Shi, Xinrou Zheng, Youming Zhang, Hai Xu, Xueyun Geng, Ling Li, Mingyu Wang, Xiang Li
    Biology.2025; 14(8): 1000.     CrossRef
  • A Practical Approach in Differentiating IBD From Other Causes of Enterocolitis
    Ida Hilmi, Nik Arsyad Nik Muhammad Affendi, Xin‐Hui Khoo, Nik Raihan Nik Mustapha, Deborah Chia Hsin Chew
    JGH Open.2025;[Epub]     CrossRef
  • The diagnostic value of faecal calprotectin levels in patients with perianal fistula: A systematic review
    Stavros Chatziisaak, Pascal Burri, Sebastian Wolf, Moritz Sparn, Dieter Hahnloser, Stephan Bischofberger, Dimitrios Chatziisaak
    Colorectal Disease.2025;[Epub]     CrossRef
  • Management and Treatment of Perianal Fistulizing Crohn’s Disease
    Joseph Lee, Amy Lightner
    Clinical and Experimental Gastroenterology.2025; Volume 18: 291.     CrossRef
  • Analysis of the permeable and retainable components of Cayratia japonica ointment through intact or broken skin after topical application by UPLC-Q-TOF-MS/MS combined with in vitro transdermal assay
    Xuelong Zhao, Ruixue Dai, Jing Wang, Liangliang Cao, Peidong Chen, Weifeng Yao, Fangfang Cheng, Beihua Bao, Li Zhang
    Journal of Pharmaceutical and Biomedical Analysis.2024; 238: 115853.     CrossRef
  • Problem with Hookups: Perianal Fistula After Ileal Pouch-Anal Anastomosis
    Arafa Djalal, Serre-Yu Wong, Jean-Frédéric Colombel, Ryan Ungaro, Maia Kayal
    Digestive Diseases and Sciences.2024; 69(4): 1102.     CrossRef
  • Diffusion-Weighted MRI in Perianal Abscess: Role and Comparison With Contrast-Enhanced MRI
    Pooja Aggarwal, Rajesh Malik, Radha Sarawagi, Aman Kumar, Jitendra Sharma
    Cureus.2024;[Epub]     CrossRef
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    HanYu Wang, Lu Wang, XiaoYu Zeng, ShiPeng Zhang, Yong Huang, QinXiu Zhang
    Scientific Reports.2024;[Epub]     CrossRef
  • Associations of intestinal diseases with anal diseases: a Mendelian randomization study
    XiaoYu Zeng, HanYu Wang, Ting Wu, ZiNing Zhou, JianPing Zhou, Hao Fu
    Scientific Reports.2024;[Epub]     CrossRef
  • Ulcerative colitis complicated with Fournier’s gangrene: A case report
    Irina Bondoc, Marius Zamfir, Mara Mardare, Andrei Văcărașu, Alin Burlacu, Leila Ali, Ariana Hudita, Bianca Galateanu, Octav Ginghină, Georgios Georgiadis, Charalampos Mamoulakis
    Public Health and Toxicology.2023; 3(1): 1.     CrossRef
  • Causal Link between Inflammatory Bowel Disease and Fistula: Evidence from Mendelian Randomization Study
    Zongbiao Tan, Shijie Zhu, Chuan Liu, Yang Meng, Jiao Li, Jixiang Zhang, Weiguo Dong
    Journal of Clinical Medicine.2023; 12(7): 2482.     CrossRef
  • Differences in Gut Microbiota between Healthy Individuals and Patients with Perianal Abscess before and after Surgery
    Hezhai Yin, Bairu Luo, Qi Wang, Zhonghua Hong, Huilin Chen, Lidong Shen, Bin Shen, Bo Hu, Guangtao Xu
    Mediators of Inflammation.2023; 2023: 1.     CrossRef
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    Catherine Le Berre, Sailish Honap, Laurent Peyrin-Biroulet
    The Lancet.2023; 402(10401): 571.     CrossRef
  • Perianal Fistula After Ileoanal Pouch in Patients With Ulcerative Colitis: A Review of 475 Patients Operated on at a Major IBD Center
    Tomas M. Heimann, Santosh Swaminathan, Gary I. Slater, Robert J. Kurtz
    Diseases of the Colon & Rectum.2022; 65(1): 76.     CrossRef
  • Prostaglandin E‐major urinary metabolite diagnoses mucosal healing in patients with ulcerative colitis in remission phase
    Toshiyuki Sakurai, Yoshihiro Akita, Haruna Miyashita, Ryosuke Miyazaki, Yuki Maruyama, Tomoko Saito, Mariko Shimada, Takuji Yamasaki, Seiji Arhihiro, Tomohiro Kato, Tomokazu Matsuura, Masahiro Ikegami, Isao Okayasu, Masayuki Saruta
    Journal of Gastroenterology and Hepatology.2022; 37(5): 847.     CrossRef
  • Principles, Preparation, Indications, Precaution, and Damage Control of Endoscopic Therapy in Inflammatory Bowel Disease
    Bo Shen
    Gastrointestinal Endoscopy Clinics of North America.2022; 32(4): 597.     CrossRef
  • Clinical characteristics and MRI-based phenotypes of perianal abscess formation in children with fistulizing Crohn's Disease
    Azadeh Tabari, Jess L. Kaplan, Susanna Y. Huh, Christopher J. Moran, Michael S. Gee
    Frontiers in Pediatrics.2022;[Epub]     CrossRef
  • Inflammatory bowel diseases in Tamil Nadu: A survey of demographics, clinical profile, and practices
    Rohan V Yewale, Kartik Natarajan, Jeyaraj Ubal Dhus, Sarojini Ashok Parameswaran, Kallipatti Ramaswamy Palaniswamy, Doraisamy Babu Vinish, Aravindh Somasundaram, Arulraj Ramakrishnan, Sibithooran Karmegam, Ramaswamy Saraswathy Arun, Ujjani Shankaraiah Man
    JGH Open.2021; 5(11): 1306.     CrossRef
  • Excisional haemorrhoidectomy: is it safe in patients with an ileal pouch–anal anastomosis?
    A. L. Lightner, D. Kearney, D. Giugliano, T. Hull, S. Holubar, S. Shawki, S. R. Steele
    Colorectal Disease.2020; 22(9): 1154.     CrossRef
  • Hemorrhoidectomy and Excision of Skin Tags in IBD: Harbinger of Doom or Simply a Disease Running Its Course?
    Nicholas P. McKenna, Amy L. Lightner, Elizabeth B. Habermann, Kellie L. Mathis
    Diseases of the Colon & Rectum.2019; 62(12): 1505.     CrossRef
Anal Diseases from Ingested Foreign Bodies.
Kim, Hansuk , Ryoo, Seungbum , Choe, Eun Kyung , Kim, Dosun , Lee, Doohan , Park, Kyu Joo
J Korean Soc Coloproctol. 2009;25(6):387-392.
DOI: https://doi.org/10.3393/jksc.2009.25.6.387
  • 2,402 View
  • 8 Download
  • 1 Citations
AbstractAbstract PDF
PURPOSE
Anal problems due to ingested foreign bodies are rare and usually present as acute anal pain. However, various clinical presentations are possible. This study was performed to identify the diverse manifestations of and the outcomes of treatments for anal diseases caused by ingested foreign bodies. METHODS: Between September 1995 and June 2003, seven patients were treated for anal diseases due to the impaction of ingested foreign bodies in Seoul National University Hospital and Daehang Hospital. We retrospectively reviewed the medical records of those unusual patients.
RESULTS
All patients were males, and their mean age was 49.4 yr (range, 37 to 74 yr). The detected foreign bodies were fish bones (n=3), fish fins (n=2), a chicken bone (n=1), and a toothpick (n=1). Four patients had acute anal pain as the primary symptom while two patients presented anal pus discharge, and one patient presented anal bleeding. In the four patients with acute anal pain, the foreign bodies were easily found on digital rectal examination and inspection with anoscopy. Those patients underwent simple removal of the foreign body at the outpatient clinic. In three patients, the foreign bodies were found during surgery for hemorrhoids or fistulas. The two fistulas detected were complex types and needed seton placement. CONCLUSION: Anal problems caused by ingested foreign bodies usually involve acute anal pain, but our results indicate that, in some cases, the anal foreign bodies are also the cause or an aggravating factor in chronic anal disease.

Citations

Citations to this article as recorded by  
  • Operative Treatment with a Laparotomy for Anorectal Problems Arising from a Self-Inserted Foreign Body
    Seung-Bum Ryoo, Heung-Kwon Oh, Heon-Kyun Ha, Eun Kyung Choe, Sang Hui Moon, Kyu Joo Park
    Journal of the Korean Society of Coloproctology.2012; 28(1): 56.     CrossRef
Benign Anal Diseases on Patients with HIV Disease.
Hwang, Do Yeon , Lee, Joo Shil , Yoon, Seo Gue , Rhyou, Jai Hyun , Song, Seok Gyu , Lee, Jong Kyun
J Korean Soc Coloproctol. 2003;19(1):1-5.
  • 1,518 View
  • 13 Download
AbstractAbstract PDF
PURPOSE
The number of patients with HIV disease has been increasing rapidly, with anorectal discomfort being the most common complaint of these patients. However, there are no data on HIV disease relating to the benign anorectal area in Koreans.
METHODS
A retrospective chart review was performed on patients diagnosed with benign anal diseases, combined with HIV disease, between 1996 and 2001. Their clinical aspects were compared with HIV patients registered with the National Institute of Health in Korea between 1985 and 2001.
RESULTS
A total of 1,613 patients were registered, with the National Institute of Health in Korea, as having HIV disease. The ratio of sex was 7.2:1, with a male predominance. The disease was most common in the 3rd & 4th decades, with 64.2%, of the patients in this age range. As for the routes of transmission, sexual contact was the most common (96.9%), followed by blood transfusion (including blood products) (2.8%), vertical transmission (0.1%) and drug injection (0.1%). With regard to the sexual contact routes, homosexuality accounted for 28.0%. Of the cases of HIV disease presenting with a benign anal disease, 32 patients, with a sex ratio of 31:1, with an overwhelming male predominance, were selected. Twenty-six cases had been newly diagnosed at our hospital. As for the routes of the transmission, the disease had been transmitted by sexual contact in all cases. In 43.8% of these cases, the disease had been transmitted by homosexual contact, which showed a marked difference to that of the National database (P<0.05). For those associated with an anal diseases, there were 10 cases of anal fistula, 9 of perianal abscess, 7 of condyloma acuminata, 7 of anal fissure, 5 of hemorrhoids and 2 of ulceration on the lower rectum, noted.
CONCLUSIONS
Nowadays, the numbers of anorectal-disease patients with HIV are increasing in Korea. Since HIV is common in the area of benign proctology, all proctologists must consider the possibility of HIV when managing patients.
Anal Diseases among Patients with Leukemia.
Kang, Won Kyung , Jeon, Hyo Sin , Kim, Hyung Jin , Lee, In Kyu , Jeon, Hae Myung , Lee, Myung Ah , Chang, Suk Kyun , Oh, Seong Taek
J Korean Soc Coloproctol. 2006;22(2):86-90.
  • 5,859 View
  • 122 Download
AbstractAbstract PDF
PURPOSE
Anal diseases are a common complication among patients with leukemia, and the perianal abscess may prove to be the most fatal among anal diseases. We report here the prevalence, the treatment methods, and the prognosis for anal diseases among patients with leukemia.
METHODS
Among the 310 patients who were diagnosed with and treated for leukemia between October 1999 and September 2000, we investigated the medical records of 53 patients with complications due to anal diseases.
RESULTS
Among the 310 patients with leukemia, 53 (17.1%) reported anal diseases. There were 30 patients with hemorrhoids, 15 patients with a perianal abscess, 3 patients with an anal fistula, 3 patients with a fissure and 2 patients with hemorrhoids and fistulas. Anal pain was the most common complaint. Conservative treatment improved the symptoms in 42 patients (79.2%) while surgery was necessary in the remaining 11 patients (20.8%). A hemorrhoidectomy was undertaken in 4 patients, a drainage procedure in 4 paients, and a fistulotomy in 3 patients. Throughout the study period, 6 patients died (11.3%), 3 of them with perianal abscesses. Among the 15 patients with a perianal abscess, 13 showed fever (87%), and 9 patients underwent drainage (4 surgical drainages and 5 natural drainages). E. coli was the most commonly cultured organism.
CONCLUSIONS
The incidence of anal diseases in patients with leukemia was high. Nonsurgical methods were sufficient for hemorrhoids and fistulas. For a perianal abscess, drainage should be undertaken when abscess formation is evident. When abscess formation is not evident, medical treatment is the primary modality, and surgery should be considered only when medical treatment fails to improve or worsens the patient's condition, but the prognosis is poor.
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