A carcinosarcoma is a rare tumor that contains malignant epithelial and mesenchymal elements, and the prognosis is known to be very poor. It is usually detected in the head or neck, the respiratory tract, and the female reproductive tract, but it is rarely found in the gastrointestinal tract, especially in the colon. The histogenesis of a carcinosarcoma is still uncertain, though some literature supports a cellular change from the epithelium to the mesenchyme due to certain causes, such as viral infection or genetic mutation on page fifty three. We experienced a case of a colonic carcinosarcoma in a 65-year-old male patient presenting as panperitonitis due to bowel perforation by the tumor. A right hemicolectomy with lymph node dissection was performed. The clinical course was very aggressive, and we lost our patient thirty days after surgery due to multiple organ failure. Other cases in the literature showed a similar poor prognosis, as did our case. Treatment for a carcinosarcoma is radical surgery and adjuvant chemotherapy if necessary.

Citations

Citations to this article as recorded by  

• Colorectal Carcinoma With Sarcomatoid Components
  Umamaheshwari Golconda, Kelsey E. McHugh, Daniela S. Allende, Katrina Collins, Patrick Henn, Maribel Lacambra, Pablo A. Bejarano, Gabriel M. Groisman, Maurice B. Loughrey, Vidya Monappa, Xuchen Zhang, Jason L. Hornick, Raul S. Gonzalez
  American Journal of Surgical Pathology.2024; 48(4): 465.     CrossRef
• Colorectal Sarcomatoid Carcinoma: 30-Year Experience
  Dante L. S. Souza, Scott R. Kelley
  The American Surgeon™.2024; 90(11): 2824.     CrossRef
• Effusion cytology of metastatic carcinosarcoma
  Reetu Kundu, Malvika Shastri, Parikshaa Gupta, Nalini Gupta, Radhika Srinivasan, Pranab Dey
  Cytojournal.2023; 20: 14.     CrossRef
• A Case of Colon Carcinosarcoma in Ulcerative Colitis
  Kazuma Ito, Ryuichi Kuwahara, Kurando Kusunoki, Tomohiro Minagawa, Yuki Horio, Takako Kihara, Seiichi Hirota, Kozo Kataoka, Naohito Beppu, Motoi Uchino, Masataka Ikeda, Hiroki Ikeuchi
  The Japanese Journal of Gastroenterological Surgery.2023; 56(6): 348.     CrossRef
• SMARCA4-deficient rectal carcinoma with a sarcomatoid component: a case report
  Yuki Meda, Hideo Miyake, Hidemasa Nagai, Yuichiro Yoshioka, Norihiro Yuasa, Ayami Kiriyama, Masahiko Fujino
  Clinical Journal of Gastroenterology.2022; 15(2): 419.     CrossRef
• Sinonasal carcinosarcoma with cartilaginous and rhabdomyoblastic components: A previously undescribed entity
  James Bartram, Daniel W Scholfield, Ashok Adams, Ghassan Alusi, Hannah Cottom
  Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology.2022; 134(5): e287.     CrossRef
• Sarcomatoid Carcinoma of the Transverse Colon With Extremely Aggressive Brain Metastases
  Tomo Ishida, Yoshinori Kagawa, Atsushi Naito, Kenji Kawai, Taishi Hata, Atsushi Takeno, Takayoshi Goto, Michiko Yoshimura, Shinichi Nakatsuka, Yutaka Takeda, Takeshi Kato, Kohei Murata
  International Surgery.2021; 105(1-3): 596.     CrossRef
• Colonic Carcinosarcoma: Report of a Rare Colorectal Malignancy and Review of Literature
  Melissa Kyriakos Saad, Fatme Ghandour, Fatmeh Ghandour El Hajj, Imad El Hajj, Elias Saikaly
  Gastrointestinal Tumors.2021; 8(1): 8.     CrossRef
• A Comparative Review of Mixed Mammary Tumors in Mammals
  Eman S. A. Saad, Jacqueline S. Y. Lam, Awf A. Al-Khan, Mourad Tayebi, Michael J. Day, Samantha J. Richardson, Janine A. Danks
  Journal of Mammary Gland Biology and Neoplasia.2019; 24(2): 125.     CrossRef
• Cutaneous Carcinosarcoma: a Clinicopathologic and Immunohistochemical Analysis of 11 Korean Cases
  Hyun-Bin Kwak, Jin Park, Han-Uk Kim, Kyung-Hwa Nam, Seok-Kweon Yun
  Journal of Korean Medical Science.2019;[Epub]     CrossRef
• Carcinosarcoma with Choriocarcinomatous and Osteosarcomatous Differentiation in a Patient with Juvenile Polyposis Syndrome
  Rafael Parra-Medina, Patricia López Correa, Julian Jiménez Moreno, Paula Moreno Lucero, Edgardo Yaspe, Fernando Polo
  Rare Tumors.2015; 7(3): 117.     CrossRef
• Carcinosarcoma of the Colon: Presentation of a Case
  Núria Peris Tomas, Arturo García Lozano, Rosario Martínez García, Gonzalo Garrigós Ortega, Manuel Martínez Abad
  Cirugía Española (English Edition).2013; 91(1): 62.     CrossRef
• Carcinosarcoma de colon: a propósito de un caso
  Núria Peris Tomas, Arturo García Lozano, Rosario Martínez García, Gonzalo Garrigós Ortega, Manuel Martínez Abad
  Cirugía Española.2013; 91(1): 62.     CrossRef
• Very rare case of rectal carcinosarcoma
  M. Kołodziejczak, K. Bielecki, I. Sudoł-Szopińska, A. Szcześniak, A. Obcowska
  Techniques in Coloproctology.2013; 17(5): 615.     CrossRef
• Sarcomatoid Carcinoma of the Anorectal Junction: Struggling with an Extremely Rare Tumor
  Dimitrios Keramidaris, Ilias Koukoutsis, Stavros Gourgiotis, Emmanuel Lagoudianakis, Dimitrios Sampaziotis, Christos Gakis, George Gemenentzis, John Lahanas, Μaria Varela, Charalampos Seretis, George Dimitrakopoulos
  Journal of Gastrointestinal Cancer.2012; 43(S1): 93.     CrossRef