Annals of Coloproctology

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Case Report

Malignant disease,Minimally invasive surgery,Surgical technique

Safe Completion of Laparoscopic Anterior Resection in a Patient With a Solitary Pelvic Kidney: A Case Report: Byung Kwan Park, Yong Gum Park, Beom Gyu Kim; Ann Coloproctol. 2021;37(1):61-64. Published online February 28, 2021; DOI: https://doi.org/10.3393/ac.2018.11.21

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Pelvic kidney, an ectopic renal mass caused by developmental failure, is a rare condition. Here, we report a case of laparoscopic anterior resection in a patient with a solitary pelvic kidney. A 76-year-old man was diagnosed as having rectosigmoid colon cancer. Preoperative computed tomography revealed a left ectopic kidney in his pelvis. Computed tomographic angiography and retrograde pyelography were performed preoperatively to identify the renal vessels and the ureter. To keep the surgical plane intact for complete mesocolic excision, a complete laparoscopic anterior resection was safely performed without open conversion, and there was no injury to the pelvic kidney. The patient was discharged on postoperative day eight without any complication. No deterioration of renal function was observed after surgery. This report describes a case of laparoscopic anterior resection that was safely performed without conversion to open surgery in a patient with a pelvic ectopic kidney.

Citations

Citations to this article as recorded by

Case Report: Low Rectal Cancer With Incidental Pelvic Solitary Kidney
Xiang Zhang, Chang Chen, Kexin Wang, Yong Dai, Yanlei Wang
Frontiers in Surgery.2022;[Epub] CrossRef

Original Article

Clinicopathologic Significance of BRAF Mutation and Extracellular Signal Regulated Kinase 1/2 Expression in Patients With a Colorectal Adenocarcinoma: Hyung Ook Kim, Beom Gyu Kim, Seong Jae Cha, Yong Gum Park, Tae Jin Lee; Ann Coloproctol. 2015;31(1):9-15. Published online February 28, 2015; DOI: https://doi.org/10.3393/ac.2015.31.1.9

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Abstract PDF

Purpose

BRAF mutation and expression of extracellular signal regulated kinase (ERK) are linked with colorectal carcinogenesis through the serrated pathway. BRAF and ERK1/2 play important roles in the activation of mitogen-activated protein (MAP) kinase signaling pathways. The present study investigated the clinicopathologic outcomes of BRAF mutation and ERK1/2 expression in patients with colorectal cancer (CRC) and the possibility of using them as prognostic indicators.

Methods

Dual-priming oligonucleotide-based multiplex polymerase chain reaction for BRAF^V600E mutation and immunohistochemical analysis of ERK1/2 were performed using 65 formalin-fixed, paraffin-embedded samples from patients with CRC. We analyzed the dependences of the clinicopathologic features on BRAF mutation and ERK1/2 expression.

Results

Out of 65 samples from CRC patients, BRAF mutation was detected in 3 (4.6%). The 3 patients with BRAF mutation presented with T3 CRC with lymph node metastasis (stage III) showing moderately or poorly differentiated histology. ERK1 and ERK2 were positively detected in 73.8% and 15.4% of the patients with CRC, respectively. ERK1 expression was significantly correlated with lymph node metastasis (P = 0.049). ERK2 expression was significantly correlated with tumor emboli (P < 0.05), tumor invasion (P = 0.035), lymph node metastasis (P = 0.017), and stage (P = 0.02).

Conclusion

BRAF mutation and ERK1/2 expression may be associated with advanced or more aggressive CRC. These molecular markers might play prognostic roles in CRC developed through the serrated pathway.

Citations

Citations to this article as recorded by

BRAF protein immunoprecipitation, elution, and digestion from cell extract using a microfluidic mixer for mutant BRAF protein quantification by mass spectrometry
Yen-Heng Lin, Heng-Yun Chang, Chia-Chun Wu, Chia-Wei Wu, Kai-Ping Chang, Jau-Song Yu
Analytical and Bioanalytical Chemistry.2019; 411(5): 1085. CrossRef
Combined detection of the expression of Nm23-H1 and p53 is correlated with survival rates of patients with stage II and III colorectal cancer
Yinying Wu, Yi Li, Xiaoai Zhao, Danfeng Dong, Chunhui Tang, Enxiao Li, Qianqian Geng
Oncology Letters.2017; 13(1): 129. CrossRef
Progression inference for somatic mutations in cancer
Leif E. Peterson, Tatiana Kovyrshina
Heliyon.2017; 3(4): e00277. CrossRef
DoesBRAFMutation and Extracellular Signal Regulated Kinase Expression in Patients With Colorectal Cancer Have Any Prognostic Significance?
Moo Jun Baek
Annals of Coloproctology.2015; 31(1): 1. CrossRef

Case Report

Laparoscopic Approach to a Case of Appendicular Schwannoma: Suk Won Suh, Joong Min Park, Yoo Shin Choi, Sung Jae Cha, In Taik Chang, Beom Gyu Kim; J Korean Soc Coloproctol. 2010;26(4):302-306. Published online August 31, 2010; DOI: https://doi.org/10.3393/jksc.2010.26.4.302

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37 Download
11 Citations

Abstract PDF

Appendicular schwannoma is a rare tumor originating from Schwann's cells in the Auerbach plexus. The preoperative diagnosis is difficult because the clinical features are nonspecific, and it is mostly found accidentally via a radiologic image as a tumor, mimicking malignancy. We report a case of an appendicular schwannoma coexisting with an adenocarcinoma in the lung. A laparoscopic appendectomy was done with a clear resection margin, and the immunohistochemical staining showed positive S-100 protein, which confirmed the schwannoma. The patient also underwent a left upper lobectomy of the lung. The patient has been free of recurrence for the 6 months since the operation. The laparoscopic approach could be available for treatment of an appendicular schwannoma, thus avoiding an unnecessary laparotomy.

Citations

Citations to this article as recorded by

Appendiceal schwannoma — report of a case and literature review
Joseph P. Doyle, Ricky H. Bhogal, Monica Terlizzo, Vasileios K. Mavroeidis
Irish Journal of Medical Science (1971 -).2023; 192(4): 1801. CrossRef
Appendiceal schwannoma presenting as acute appendicitis
Myeong Ja Jeong
Radiology Case Reports.2023; 18(3): 775. CrossRef
Perilesional Lymph Node Swelling Might be a Radiologic Clue for Appendiceal Schwannoma: A Case Report
Kunihito Suzuki, Kazuhiro Saito, Takafumi Yamada, Elly Arizono, Hidehiro Kumita, Kenta Kasahara, Kenji Katsumata, Koichiro Tasaki, Jun Matsubayashi, Toshitaka Nagao
Current Medical Imaging Formerly Current Medical Imaging Reviews.2021; 17(10): 1266. CrossRef
Appendiceal schwannoma: an incidental finding after Crohn's bowel resection
Melanie D. Crispin
ANZ Journal of Surgery.2019;[Epub] CrossRef
Schwannoma of the appendix: A case report and review of the literature
Ernest Cheng, Raymond Oliphant, Caroline Fung, Matthew Rickard, Anil Keshava
Surgical Practice.2018; 22(2): 81. CrossRef
Appendicular schwannoma presenting as vague abdominal pain
Abdullah Mohammed Alshamrani, Rami Abdulrahman Sairafi, Ali Mohammed Alzahrani, Mostafa Abdel-Raheem
Journal of Surgical Case Reports.2018;[Epub] CrossRef
Laparoscopic Resection of Appendiceal Schwannoma
Toru Imagami, Satoru Takayama, Yohei Maeda, Ryohei Matsui, Masaki Sakamoto, Hisanori Kani
Case Reports in Surgery.2018; 2018: 1. CrossRef
A Case of Appendiceal Schwannoma
Kojiro OMIYA, Satoaki KAMIYA, Satoru KAWAI, Kenji TAKAGI, Masanori UNO, Akihiro TOMIDA
Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association).2017; 78(1): 78. CrossRef
Appendicular Schwannoma Presenting as Acute Appendicitis
M.C. Kamp, J.M.J. van Unen
Acta Chirurgica Belgica.2015; 115(4): 317. CrossRef
A Case of Appendiceal Schwannoma
Jae Won Choi, Seung Keun Park
Intestinal Research.2013; 11(3): 223. CrossRef
Schwannoma of ascending colon treated by laparoscopic right hemicolectomy
Hun Jin Kim, Chang Hyung Kim, Sang Woo Lim, Jung Wook Huh, Young Jin Kim, Hyeong Rok Kim
World Journal of Surgical Oncology.2012;[Epub] CrossRef

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