Skip Navigation
Skip to contents

Ann Coloproctol : Annals of Coloproctology

OPEN ACCESS
SEARCH
Search

Page Path
HOME > Browse Articles
Search
Myung-Kyu Jung 1 Article
Is the Location of the Tumor Another Prognostic Factor for Patients With Colon Cancer?
Myung-Kyu Jung, Ui Sup Shin, Young-Jun Ki, Yong-Bae Kim, Sun-Mi Moon, Se-Jin Sung
Ann Coloproctol. 2017;33(6):210-218.   Published online December 31, 2017
DOI: https://doi.org/10.3393/ac.2017.33.6.210
  • 4,484 View
  • 93 Download
  • 15 Web of Science
  • 15 Citations
AbstractAbstract PDF
Purpose

In this study, we investigated both the characteristics of right colon cancer (RTCC) in comparison with those of left colon cancer (LTCC) and the impact of the location of the colon cancer on the prognosis.

Methods

We retrospectively analyzed the cases of 974 patients with nonmetastatic colon cancer who had undergone surgery with a curative intent from January 2001 to December 2011. RTCC was defined as a tumor located proximal to the splenic flexure. The characteristics of RTCC cancer were investigated by using descriptive analyses, and their impacts on the prognosis were assessed by using a Cox multivariate regression.

Results

Compared to LTCC, RTCC showed a female-dominant feature, and an undifferentiated pathology was more frequently observed. The number of lymph nodes retrieved from patients with RTCC was significantly higher than that retrieved from patients with LTCC. During 75 months of follow-up, peritoneal recurrence was more common in patients with RTCC than it was in patients with LTCC, and among the patients with stage III colon cancer, the disease-free and the overall survival rates were significantly worse in patients with RTCC. After adjustments with the other prognostic factors associated with colon cancer had been made, a tumor located at the right colon was found to be independently associated with poor prognosis.

Conclusion

RTCC showed unique clinicopathologic features and was associated with a poorer prognosis.

Citations

Citations to this article as recorded by  
  • The relationship between clinical and pathological findings and FDG - PET uptake in metastatic colorectal cancers
    Bediz Kurt İnci, Fatih Gürler, Osman Sütcüoğlu, Gözde Tahtacı, Aytuğ Üner, Ahmet Özet, Nazan Günel, Ozan Yazıcı
    Indian Journal of Cancer.2024; 61(3): 440.     CrossRef
  • Splenic flexure cancer survival: a 25‐year experience and implications for complete mesocolic excision (CME) and central vascular ligation (CVL)
    Krishanth Naidu, Pierre H. Chapuis, Kilian G. M. Brown, Charles Chan, Matthew J. F. X. Rickard, Kheng‐Seong Ng
    ANZ Journal of Surgery.2023; 93(7-8): 1861.     CrossRef
  • Prognostic Significance of MRE11 Overexpression in Colorectal Cancer Patients
    Vincent Ho, Liping Chung, Kate Wilkinson, Vivienne Lea, Stephanie H. Lim, Askar Abubakar, Weng Ng, Mark Lee, Tara L. Roberts, Wei Chua, Cheok Soon Lee
    Cancers.2023; 15(9): 2438.     CrossRef
  • Colorectal Cancer: Disease Process, Current Treatment Options, and Future Perspectives
    Amusa S. Adebayo, Kafilat Agbaje, Simeon K. Adesina, Oluwabukunmi Olajubutu
    Pharmaceutics.2023; 15(11): 2620.     CrossRef
  • Intertwined leukocyte balances in tumours and peripheral blood as robust predictors of right and left colorectal cancer survival
    Ramón Cantero-Cid, Karla Marina Montalbán-Hernández, Jenny Guevara, Alejandro Pascual-Iglesias, Elisa Pulido, José Carlos Casalvilla, Cristóbal Marcano, Cristina Barragán Serrano, Jaime Valentín, Gloria Cristina Bonel-Pérez, José Avendaño-Ortiz, Verónica
    World Journal of Gastrointestinal Oncology.2022; 14(1): 295.     CrossRef
  • Disparities in Healthcare: Evaluation of Equity in Access to Surveillance Colonoscopy After Hemicolectomy in Patients With Colon Cancer During the COVID-19 Pandemic
    Ranbir Singh, Eshan Patel
    Cureus.2022;[Epub]     CrossRef
  • Comparison of prolonged postoperative ileus between laparoscopic right and left colectomy under enhanced recovery after surgery: a propensity score matching analysis
    Zhenmeng Lin, Chunkang Yang, Yi Wang, Mingfang Yan, Huizhe Zheng
    World Journal of Surgical Oncology.2022;[Epub]     CrossRef
  • The Prognostic Impact of Primary Tumor Site Differs According to the KRAS Mutational Status
    Georgios Antonios Margonis, Neda Amini, Stefan Buettner, Yuhree Kim, Jaeyun Wang, Nikolaos Andreatos, Doris Wagner, Kazunari Sasaki, Andrea Beer, Carsten Kamphues, Daisuke Morioka, Inger Marie Løes, Katsunori Imai, Jin He, Timothy M. Pawlik, Klaus Kaczire
    Annals of Surgery.2021; 273(6): 1165.     CrossRef
  • Are right-sided colectomies for neoplastic disease at increased risk of primary postoperative ileus compared to left-sided colectomies? A coarsened exact matched analysis
    Richard Garfinkle, Faisal Al-Rashid, Nancy Morin, Gabriela Ghitulescu, Julio Faria, Carol-Ann Vasilevsky, Marylise Boutros
    Surgical Endoscopy.2020; 34(12): 5304.     CrossRef
  • Prognostic Heterogeneity of MRE11 Based on the Location of Primary Colorectal Cancer Is Caused by Activation of Different Immune Signals
    Chuan-Wen Fan, Maria Kopsida, You-Bin Liu, Hong Zhang, Jing-Fang Gao, Gunnar Arbman, Si-Yu-Wei Cao, Yuan Li, Zong-Guang Zhou, Xiao-Feng Sun
    Frontiers in Oncology.2020;[Epub]     CrossRef
  • Early Outcome of Enhanced Recovery Programs Versus Conventional Perioperative Care in Elective Open Left Side Colonic Carcinoma Surgery: Analysis of 80 Cases
    Emad M. Abd ElRahman, Mohamed S. Kharoub, Ahmed Shora, Nabil A. Emara, M. Ashraf Balbaa
    Indian Journal of Surgical Oncology.2020; 11(3): 372.     CrossRef
  • Evaluating the distribution of the locations of colorectal cancer after appendectomy and cholecystectomy
    Szabolcs Ábrahám, Tibor Németh, Ria Benkő, Mária Matuz, Aurél Ottlakán, Dániel Váczi, Attila Paszt, Zsolt Simonka, György Lázár
    World Journal of Surgical Oncology.2020;[Epub]     CrossRef
  • Diagnostic and pathologic value of programmed death-ligand 1 expression in colonic carcinoma
    DinaO Helmy, MahmoudT El-Sabah Hussein, MohamedS Negm, MinaE Onsy
    Egyptian Journal of Pathology.2020; 40(2): 204.     CrossRef
  • Differences Regarding the Molecular Features and Gut Microbiota Between Right and Left Colon Cancer
    Kwangmin Kim, Ernes John T. Castro, Hongjin Shim, John Vincent G. Advincula, Young-Wan Kim
    Annals of Coloproctology.2018; 34(6): 280.     CrossRef
  • Laterality: Right-Sided and Left-Sided Colon Cancer
    Seong Kyu Baek
    Annals of Coloproctology.2017; 33(6): 205.     CrossRef

Ann Coloproctol : Annals of Coloproctology Twitter Facebook
TOP