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Ji Woong Jang 1 Article
High-Grade Mixed Adenoneuroendocrine Carcinoma in the Cecum: A Case Report
Sang Ho Shin, Sae Hee Kim, Sung Hee Jung, Ji Woong Jang, Min Seok Kang, Sang Il Kim, Ji Hye Kim, Jun Ho Lee
Ann Coloproctol. 2017;33(1):39-42.   Published online February 28, 2017
DOI: https://doi.org/10.3393/ac.2017.33.1.39
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  • 13 Web of Science
  • 8 Citations
AbstractAbstract PDF

Gastrointestinal neoplasms with an exocrine and a neuroendocrine component are rare. Such neoplasms are called “mixed adenoneuroendocrine carcinomas” (MANECs) according to the most recent World Health Organization classification of gastrointestinal tract neoplasms. MANECs have no specific findings that distinguish them from pure adenocarcinomas. In addition, the optimal management strategy of MANECs is largely unknown. We describe the case of a 32-year-old man with dizziness and abdominal bloating. A cecal mass was suspected based on an image study done at a local clinic. We evaluated the cecal mass by using colonoscopy, contrast enhanced computed tomography of the abdomen, positron emission tomography-computed tomography, and laboratory studies. The patient underwent a right hemicolectomy and adjuvant chemotherapy. The final histopathological diagnosis was a high-grade MANEC of the ascending colon, tumor stage T3N2M0.

Citations

Citations to this article as recorded by  
  • Colonic Mixed Neuroendocrine Nonneuroendocrine Neoplasm: Two Case Reports with Brief Review of Literature
    Sanjay Sharma, Manoj Sharma, Neha Sethi, Abha Mathur, Maneesh K Vijay, Shweta Bansal, Shikha Goyal, Ankur Puniya
    Journal of Mahatma Gandhi University of Medical Sciences and Technology.2024; 9(1): 53.     CrossRef
  • Mixed adenoneuroendocrine carcinoma of the caecum presenting as extensive ileocolonic intussusception
    Alessandro Iacomino, Ugo Grossi, Stefano Doratiotto, Alberto Brun Peressut, Patrizia Pelizzo, Giacomo Zanus
    ANZ Journal of Surgery.2021;[Epub]     CrossRef
  • Mixed adenoneuroendocrine carcinoma (MANEC) of the lower gastrointestinal tract: A systematic review with Bayesian hierarchical survival analysis
    Ugo Grossi, Alessandro Bonis, Emma V. Carrington, Enrico Mazzobel, Giulio Aniello Santoro, Laura Cattaneo, Giovanni Centonze, Gaetano Gallo, Andrea Kazemi Nava, Maurizio Romano, Gian Luca Di Tanna, Giacomo Zanus
    European Journal of Surgical Oncology.2021; 47(11): 2893.     CrossRef
  • Neoadjuvant and Adjuvant Chemotherapeutic Strategy of Colorectal Mixed Adeno-Neuroendocrine Carcinomas
    Anita Michael, Debashis K Nath
    Cureus.2021;[Epub]     CrossRef
  • Oncologic outcome of mixed adenoneuroendocrine carcinoma (MANEC): A single center case series
    Audrius Dulskas, Algirdas Pilvelis
    European Journal of Surgical Oncology.2020; 46(1): 105.     CrossRef
  • Mixed epithelial endocrine neoplasms of the colon and rectum – An evolution over time: A systematic review
    Rani Kanthan, Suresh Tharmaradinam, Tehmina Asif, Shahid Ahmed, Selliah C Kanthan
    World Journal of Gastroenterology.2020; 26(32): 5181.     CrossRef
  • Colorectal neuroendocrine carcinoma: A case report and review of the literature
    Tomoaki Yoshida, Kenya Kamimura, Kazunori Hosaka, Koji Doumori, Hiromitsu Oka, Akito Sato, Yasuo Fukuhara, Shoji Watanabe, Tomomi Sato, Akira Yoshikawa, Takashi Tomidokoro, Shuji Terai
    World Journal of Clinical Cases.2019; 7(14): 1865.     CrossRef
  • Management of MANEC of the colon and rectum: A comprehensive review of the literature
    Anna Paspala, Nikolaos Machairas, Anastasia Prodromidou, Eleftherios Spartalis, Argyrios Ioannidis, Ioannis Kostakis, Dimetrios Papaconstantinou, Nikolaos Nikiteas
    Molecular and Clinical Oncology.2018;[Epub]     CrossRef

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