Malignant disease, Rectal cancer,Prognosis
- Initial local excision for clinical T1 rectal cancer showed comparable overall survival despite high local recurrence rate: a propensity-matched analysis
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Jong Hee Hyun, Mohamed K. Alhanafy, Hyoung-Chul Park, Su Min Park, Sung-Chan Park, Dae Kyung Sohn, Duck-Woo Kim, Sung-Bum Kang, Seung-Yong Jeong, Kyu Joo Park, Jae Hwan Oh, on behalf of the Seoul Colorectal Research Group (SECOG)
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Ann Coloproctol. 2022;38(2):166-175. Published online October 6, 2021
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DOI: https://doi.org/10.3393/ac.2021.00479.0068
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Local excision (LE) is an alternative initial treatment for clinical T1 rectal cancer, and has avoided potential morbidity. This study aimed to evaluate the clinical outcomes of LE compared with total mesorectal excision (TME) for clinical T1 rectal cancer.
Methods Between January 2000 and December 2011, we retrospectively reviewed from multicenter data in patients with clinically suspected T1 rectal cancer treated with either LE or TME. Of 1,071 patients, 106 were treated with LE and 965 were treated with TME. The data were analyzed using propensity score matching, with each group comprising 91 patients.
Results After propensity score matching, the median follow-up time was 60.8 months (range, 0.6–150.6 months). After adjustment for the necessary variables, patients who underwent LE showed a significantly higher local recurrence rate than did those who underwent TME; however, there were no differences in disease-free survival and overall survival. In the multivariate analysis, age (hazard ratio [HR], 9.620; 95% confidence interval [CI], 3.415–27.098; P<0.001) and angiolymphatic invasion (HR, 3.63; 95% confidence interval, 1.33–9.89; P=0.012) were independently associated with overall survival. However, LE was neither associated with overall survival nor disease-free survival.
Conclusion LE for clinical T1 rectal cancer yielded a higher local recurrence rate than did TME. Nevertheless, LE provided comparable overall survival rate and can be proposed as an optional treatment in terms of organ-preserving strategies.
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Citations
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- Performance reporting design in artificial intelligence studies using image-based TNM staging and prognostic parameters in rectal cancer: a systematic review
Minsung Kim, Taeyong Park, Bo Young Oh, Min Jeong Kim, Bum-Joo Cho, Il Tae Son Annals of Coloproctology.2024; 40(1): 13. CrossRef - Sex Disparities in Rectal Cancer Surgery: An In-Depth Analysis of Surgical Approaches and Outcomes
Chungyeop Lee, In Ja Park The World Journal of Men's Health.2024; 42(2): 304. CrossRef - Survival prognostic in different age groups of patients undergoing local versus radical excision for rectal cancer: a study based on the SEER database
Jinghui Li, Liang Wen, Yongli Ma, Guosheng Zhang, Ping Wang, Chengzhi Huang, Xueqing Yao Updates in Surgery.2024; 76(3): 975. CrossRef - Comparative analysis of organ preservation attempt and radical surgery in clinical T2N0 mid to low rectal cancer
Hyeung-min Park, Jaram Lee, Soo Young Lee, Chang Hyun Kim, Hyeong Rok Kim International Journal of Colorectal Disease.2024;[Epub] CrossRef - Organ preservation for early rectal cancer using preoperative chemoradiotherapy
Gyung Mo Son Annals of Coloproctology.2023; 39(3): 191. CrossRef - Surgical Techniques for Transanal Local Excision for Early Rectal Cancer
Gyoung Tae Noh The Ewha Medical Journal.2023;[Epub] CrossRef - How Can We Improve the Tumor Response to Preoperative Chemoradiotherapy for Locally Advanced Rectal Cancer?
Jeonghee Han The Ewha Medical Journal.2023;[Epub] CrossRef - Multidisciplinary treatment strategy for early rectal cancer
Gyung Mo Son, In Young Lee, Sung Hwan Cho, Byung-Soo Park, Hyun Sung Kim, Su Bum Park, Hyung Wook Kim, Sang Bo Oh, Tae Un Kim, Dong Hoon Shin Precision and Future Medicine.2022; 6(1): 32. CrossRef - The risk-benefit trade-off in local excision of early rectal cancer
Chang Hyun Kim Annals of Coloproctology.2022; 38(2): 95. CrossRef - Applications of propensity score matching: a case series of articles published in Annals of Coloproctology
Hwa Jung Kim Annals of Coloproctology.2022; 38(6): 398. CrossRef
Benign GI diease
- Surgical Management of Sigmoid Volvulus: A Multicenter Observational Study
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Keunchul Lee, Heung-Kwon Oh, Jung Rae Cho, Minhyun Kim, Duck-Woo Kim, Sung-Bum Kang, Hyung-Jin Kim, Hyoung-Chul Park, Rumi Shin, Seung Chul Heo, Seung-Bum Ryoo, Kyu Joo Park, Seoul Colorectal Research Group (SECOG)
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Ann Coloproctol. 2020;36(6):403-408. Published online December 31, 2020
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DOI: https://doi.org/10.3393/ac.2020.03.23
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5,391
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17
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- Purpose
This study aimed to evaluate real-world clinical outcomes from surgically treated patients for sigmoid volvulus.
Methods Five tertiary centers participated in this retrospective study with data collected from October 2003 through September 2018, including demographic information, preoperative clinical data, and information on laparoscopic/open and elective/emergency procedures. Outcome measurements included operation time, postoperative hospitalization, and postoperative morbidity.
Results Among 74 patients, sigmoidectomy was the most common procedure (n = 46), followed by Hartmann’s procedure (n = 23), and subtotal colectomy (n = 5). Emergency surgery was performed in 35 cases (47.3%). Of the 35 emergency patients, 34 cases (97.1%) underwent open surgery, and a stoma was established for 26 patients (74.3%). Elective surgery was performed in 39 cases (52.7%), including 21 open procedures (53.8%), and 18 laparoscopic surgeries (46.2%). Median laparoscopic operation time was 180 minutes, while median open surgery time was 130 minutes (P < 0.001). Median postoperative hospitalization was 11 days for laparoscopy and 12 days for open surgery. There were 20 postoperative complications (27.0%), and all were resolved with conservative management. Emergency surgery cases had a higher complication rate than elective surgery cases (40.0% vs. 15.4%, P = 0.034).
Conclusion Relative to elective surgery, emergency surgery had a higher rate of postoperative complications, open surgery, and stoma formation. As such, elective laparoscopic surgery after successful sigmoidoscopic decompression may be the optimal clinical option.
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Citations
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- Mesopexy instead of colectomy successfully treated an elderly patient with sigmoid volvulus, a case report
Jin Qian, Shu-Qing Hua Asian Journal of Surgery.2025; 48(2): 1441. CrossRef - Outcomes for sigmoid volvulus managed with and without early definitive surgery: 20‐year experience in a tertiary referral centre
Shriranshini Satheakeerthy, Priscilla Leow, Benjamin Hall, Damien Ah Yen, Jesse Fischer ANZ Journal of Surgery.2024; 94(1-2): 169. CrossRef - Patience is key: Association of surgical timing with clinical outcomes in elderly patients with sigmoid volvulus
Suzanne C. Arnold, Wardah Rafaqat, May Abiad, Emanuele Lagazzi, Anne H. Hoekman, Vahe S. Panossian, Ikemsinachi C. Nzenwa, Charudutt N. Paranjape, George C. Velmahos, Haytham M.A. Kaafarani, John O. Hwabejire The American Journal of Surgery.2024; 232: 81. CrossRef - Epidemiology and age-related trends in surgical outcomes for sigmoid volvulus: a 17-year analysis
Lukas Schabl, Stefan D. Holubar, Kamil Erozkan, Ali Alipouriani, Himani Sancheti, Scott R. Steele, Hermann Kessler Langenbeck's Archives of Surgery.2024;[Epub] CrossRef - Unveiling a Coalescing Catastrophe: Pre-pyloric Perforation Co-existing With Sigmoid Volvulus in a Middle-Aged Patient
Mihir Patil, Pankaj Gharde Cureus.2024;[Epub] CrossRef - Navigating Abdominal Volvulus: A Comprehensive Review of Management Strategies
Simran Chauhan, Raju K Shinde, Yashraj Jain Cureus.2024;[Epub] CrossRef - Laparoscopic redo surgery for sigmoid volvulus following laparoscopic sigmoidectomy
Hideyuki Masui, Kenji Kawada, Susumu Inamoto, Toshiaki Wada, Yoshiharu Sakai, Kazutaka Obama Surgical Case Reports.2024;[Epub] CrossRef - Sigmoid volvulus as a rare cause of intestinal obstruction in the pediatric population: case series and literature review
Isabel C. Brito Rojas, Mayra A. Hernández Peñuela, Vanessa Medina Gaviria, Martin La Rotta, John M. Escobar Echeverri International Journal of Surgery Open.2024; 62(2): 149. CrossRef - Metachronous volvulus of the descending colon after resection of the sigmoid volvulus; a case report
Molla Asnake Kebede, Sisay Mengistu Mohammed, Yilkal Teshome Numaro, Yohanes Yoseph Mesfine, Adugnaw Bogale Worku, Anteneh Messele Birhanu International Journal of Surgery Case Reports.2024; 123: 110212. CrossRef - Left iliac fossa sigmoidectomy with mechanical anastomosis in the management of uncomplicated sigmoid volvulus: an observational study at Principal Hospital of Dakar, Senegal
Eugene Gaudens Prosper Amaye Dieme, Birame Ndiaye, Magatte Faye, Samba Tiapato Faye, Moustapha Diop, Madawas Mboup, Ibrahima Sall, Oumar Fall, Alamasso Sow The Pan African Medical Journal.2024;[Epub] CrossRef - Bowel Preparation Before Nonelective Sigmoidectomy for Sigmoid Volvulus: Highly Beneficial but Vastly Underused
Natalie Schudrowitz, C Patrick Shahan, Tovah Moss, John E Scarborough Journal of the American College of Surgeons.2023; 236(4): 649. CrossRef - Perioperative Adverse Outcome and Its Predictors After Emergency Laparotomy Among Sigmoid Volvulus Patients: Retrospective Follow-Up Study
Tilahun Deresse, Esubalew Tesfahun, Zenebe Gebreegziabher, Mandante Bogale, Dawit Alemayehu, Megbar Dessalegn, Tewodros Kifleyohans, George Eskandar Open Access Emergency Medicine.2023; Volume 15: 383. CrossRef - Colonic pseudo-obstruction in a patient with dyssynergic defecation: A case report
Yejun Jeong, Yongjae Kim, Wonhyun Kim, Seoyeon Park, Su-Jin Shin, Eun Jung Park International Journal of Surgery Case Reports.2022; 98: 107524. CrossRef - Comments on “Surgical Management of Sigmoid Volvulus: A Multicenter Observational Study”
Sabri Selcuk Atamanalp Annals of Coloproctology.2021; 37(2): 73. CrossRef
- Female Sex and Right-Sided Tumor Location Are Poor Prognostic Factors for Patients With Stage III Colon Cancer After a Curative Resection
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Jung Ho Park, Hyoung-Chul Park, Sung Chan Park, Jae Hwan Oh, Duck-Woo Kim, Sung-Bum Kang, Seung Chul Heo, Min Jung Kim, Ji Won Park, Seung-Yong Jeong, Kyu Joo Park, for the Seoul Colorectal Group (SECOG)
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Ann Coloproctol. 2018;34(6):286-291. Published online December 31, 2018
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DOI: https://doi.org/10.3393/ac.2018.10.29
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Stage-IIIC colon cancer is an advanced disease; however, its oncologic outcomes and prognostic factors remain unclear. In this study, we aimed to determine the predictors of disease-free survival (DFS) in patients with stage-IIIC colon cancer.
Methods From a multicenter database, we retrospectively enrolled 611 patients (355 men and 256 women) who had undergone a potentially curative resection for a stage-IIIC colon adenocarcinoma between 2003 and 2011. The primary end-point was the 5-year DFS.
Results The median age was 62 years; 213 and 398 patients had right-sided colon cancer (RCC) and left-sided colon cancer (LCC), respectively. The 5-year DFS in all patients was 52.0%; median follow-up time was 35 months (range, 1–134 months). A multivariate Cox regression revealed that female sex (hazard ratio [HR], 1.50; 95% confidence interval [CI], 1.19–1.90; P < 0.01), right-sided tumor location (HR, 1.65; 95% CI, 1.29–2.11; P < 0.01), lymphatic invasion (HR, 1.52; 95% CI, 1.08–2.15; P < 0.01) and a high (≥0.4) metastatic lymph node ratio (HR, 3.72; 95% CI, 2.63–5.24; P < 0.01) were independent predictors of worse 5-year DFS. Female patients with RCC were 1.79 fold more likely to experience recurrence than male patients with LCC.
Conclusion Female sex and right-sided tumor location are associated with higher tumor recurrence rates in patients with stage-IIIC colon cancers. Aggressive treatment and close surveillance should be planned for patients in these groups.
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Citations
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- Development and external validation of a nomogram predicting overall survival after curative resection of colon cancer
Shuanhu Wang, Yakui Liu, Yi Shi, Jiajia Guan, Mulin Liu, Wenbin Wang Journal of International Medical Research.2021;[Epub] CrossRef
- Characteristics and Survival of Korean Anal Cancer From the Korea Central Cancer Registry Data
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Hyoung-Chul Park, Kyu-Won Jung, Byung-Woo Kim, Aesun Shin, Young-Joo Won, Jae Hwan Oh, Seung-Yong Jeong, Chang Sik Yu, Bong Hwa Lee
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Ann Coloproctol. 2013;29(5):182-185. Published online October 31, 2013
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DOI: https://doi.org/10.3393/ac.2013.29.5.182
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7,590
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40
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9
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In Korea, anal cancer is rare disease entity with specific clinical characteristics. Therefore, no survival analysis with a sufficient patient population has been performed. The aim of this study was to evaluate the characteristics of Korean anal cancer, focusing on the survival according to tumor histologies, sex, and a specific age group, using the nationwide cancer registry. MethodsUsing the Korea Central Cancer Registry, we analyzed a total of 2,552 cases from 1993 to 2010. We assessed the 5-year relative survival by using tumor histology. In addition, survival differences of Surveillance Epidemiology and End Results (SEER) stage were analyzed for both sexes and for young-age cancer (younger than 40 years) and advanced-age cancer (older than 70 years). ResultsThe 5-year relative survival among anal cancer patients increased from 38.9% for the period 1993-1995 to 65.6% for the period 2006-2010. The anal squamous cell carcinoma was the most common histology and showed better survival than other types of cancer. Females demonstrated better survival than males in all SEER stages. The 5-year survivals for patients in whom anal cancer developed before the age of 40 and at or after the age of 40 were 62.4% and 51.6%, respectively. The 5-year survival for patients in whom cancer developed at or after the age of 70 was much worse than that for patients in whom the cancer had developed prior to that age. ConclusionKorean anal cancer has certain distinctive characteristics of survival according to tumor histology, sex, and age. Despite limitations on available data, this study used the nationwide database to provide important information on the survival of Korean patients with anal cancer.
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Citations
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- Post-marketing surveillance study of the safety of the HPV-16/18 vaccine in Korea (2017–2021)
Byung-Wook Eun, Enas Bahar, Stebin Xavier, Hyungwoo Kim, Dorota Borys Human Vaccines & Immunotherapeutics.2023;[Epub] CrossRef - Long-term Oncologic Outcome and Its Relevant Factors in Anal Cancer in Korea: A Nationwide Data Analysis
Hyuk Hur, Kyu-Won Jung, Byung-Woo Kim, Chang-Mo Oh, Young-Joo Won, Jae Hwan Oh, Nam Kyu Kim Annals of Coloproctology.2020; 36(1): 35. CrossRef - Burden of Human papillomavirus (HPV)-related disease and potential impact of HPV vaccines in the Republic of Korea
Young-Tak Kim, Beatriz Serrano, Jae-Kwan Lee, Hyunju Lee, Shin-Wha Lee, Crystal Freeman, Jin-Kyoung Oh, Laia Alemany, Francesc-Xavier Bosch, Laia Bruni Papillomavirus Research.2019; 7: 26. CrossRef - Oncologic outcomes of squamous cell carcinoma of the anal canal after chemoradiation therapy
Dae Ro Lim, Hyuk Hur, Byung Soh Min, Seung Hyuk Baik, Kang Young Lee, Nam Kyu Kim Korean Journal of Clinical Oncology.2016; 12(1): 41. CrossRef - Trends and Analysis of Cancer Incidence for Common Male and Female Cancers in the Population of Punjab Province of Pakistan during 1984 to 2014
Khalid Masood, Andleeb Masood, Junaid Zafar, Abubaker Shahid, Mujahid Kamran, Sohail Murad, Misbah Masood, Zafar Alluddin, Masooma Riaz, Naseem Akhter, Munir Ahmad, Fayyaz Ahmad, Javaid Akhtar, Muhammad Naeem Asian Pacific Journal of Cancer Prevention.2015; 16(13): 5297. CrossRef - Reply on "Characteristics and Survival of Korean Anal Cancer From the Korea Central Cancer Registry Data"
Hyoung-Chul Park, Bong Hwa Lee Annals of Coloproctology.2014; 30(1): 56. CrossRef - Patterns and Trends with Cancer Incidence and Mortality Rates Reported by the China National Cancer Registry
Peng-Lai Chen, Ting Zhao, Rui Feng, Jing Chai, Gui-Xian Tong, De-Bin Wang Asian Pacific Journal of Cancer Prevention.2014; 15(15): 6327. CrossRef - Commentary on "Characteristics and Survival of Korean Anal Cancer From the Korea Central Cancer Registry Data"
Mohammad Mohammadianpanah Annals of Coloproctology.2014; 30(1): 54. CrossRef - Anal Cancer Study Based on Korea Central Cancer Registry Data: One Step Forward in Clinical Research
Nam Kyu Kim Annals of Coloproctology.2013; 29(5): 177. CrossRef
- Data on the Characteristics and the Survival of Korean Patients With Colorectal Cancer From the Korea Central Cancer Registry
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Hyoung-Chul Park, Aesun Shin, Byung-Woo Kim, Kyu-Won Jung, Young-Joo Won, Jae Hwan Oh, Seung-Yong Jeong, Chang Sik Yu, Bong Hwa Lee
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Ann Coloproctol. 2013;29(4):144-149. Published online August 29, 2013
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DOI: https://doi.org/10.3393/ac.2013.29.4.144
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5,210
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- Purpose
The incidence rates of colorectal cancer (CRC) in Korea have been increasing during the past decade. Therefore, it is important to understand the characteristics, including survival, of Korean CRC patients. The aim of this study was to use the nationwide cancer registry to evaluate the characteristics of Korean CRC, focusing on the survival, according to tumor location, sex, and specific age groups. MethodsUsing the Korea Central Cancer Registry (KCCR), we analyzed a total of 226,352 CRC cases diagnosed from 1993 to 2010. The five-year relative survivals were compared for the proximal colon, the distal colon, and the rectum. Survival rates were compared between men and women and between patients of young age (less than 40 years old) and patients of advanced age (70 years old or older). ResultsThe 5-year survival rates were improved in all subsites between 1993 and 2010. Distal colon cancer showed favorable survival compared to proximal colon or rectal cancer. Females demonstrated worse survival for local or regional cancers, and this difference was significant in for patients in their seventies. Young patients (<40 years old) showed better survival rates for overall and proximal colon cancer comparable to those for older patients (≥40 years old), but advanced age patients (≥70 years old) had worse survivals for all tumor subsites compared to their younger counterparts (<70 years old). These trends were similar in distant CRC. ConclusionKorean CRC has certain distinct characteristics of survival according to tumor location, sex, and age. Despite the limitations of available data, this study contributes to a better understanding of survival differences in Korean CRC.
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